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颞骨钝性创伤后面瘫的处理和结局:系统评价。

Management and outcomes of facial paralysis from intratemporal blunt trauma: a systematic review.

机构信息

Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin and Affiliated Hospitals, Milwaukee, Wisconsin 53226, USA.

出版信息

Laryngoscope. 2010 Jul;120(7):1397-404. doi: 10.1002/lary.20943.

DOI:10.1002/lary.20943
PMID:20564723
Abstract

OBJECTIVES/HYPOTHESIS: To systematically review the existing literature on outcomes and management of facial paralysis resulting from intratemporal blunt trauma.

STUDY DESIGN

Systematic review of the literature.

METHODS

Thirty-five articles met our inclusion criteria. Outcome variables analyzed included severity of paralysis, time of onset of paralysis, surgical or nonsurgical management, steroid use, and final facial nerve function.

RESULTS

All studies were classified as level 4 evidence as defined by the Oxford Centre for Evidence-Based Medicine. There was marked variation in the quality of the studies with inconsistent outcome measures, diagnostic testing, and follow-up, thus ruling out a formal meta-analysis. In an exploratory pooling of data, 612 cases had sufficient follow-up and facial movement grading for some evaluation of trends. In 189 patients who were followed observationally, 66% achieved an outcome equivalent to House-Brackmann (HB) I, 25% achieving HB II-V, and two patients an HB VI score. Among 83 patients treated with steroids, 67% achieved HB I, 30% HB II-V, and no patients with HB VI. In 340 patients treated surgically, 23% achieved HB I postoperatively, 58% were graded as HB II-V, and 9% with HB grade VI postoperatively. No patient presenting with partial paralysis had an HB VI outcome.

CONCLUSIONS

The role of surgery versus nonsurgical interventions for this clinical entity remains inconclusive. Level 4 evidence studies predominate and are further hindered by poor description of outcome measures and incomplete data reporting. Exploratory pooling of data without formal meta-analysis suggests the need to compare any intervention to the natural course of healing, which overall appears to be favorable.

摘要

目的/假设:系统回顾关于颞骨钝性创伤导致的面瘫的结局和处理的现有文献。

研究设计

文献系统回顾。

方法

35 篇文章符合我们的纳入标准。分析的结局变量包括瘫痪的严重程度、瘫痪的发病时间、手术或非手术处理、类固醇的使用以及最终的面神经功能。

结果

所有研究均被归类为牛津循证医学中心定义的 4 级证据。研究质量存在显著差异,研究结果不一致,缺乏诊断性检测和随访,因此排除了正式的荟萃分析。在对数据的探索性汇总中,612 例有足够的随访和面部运动分级,可对某些趋势进行评估。在 189 例接受观察治疗的患者中,66%的患者达到了 House-Brackmann(HB)I 级的结果,25%的患者达到了 HB II-V 级的结果,两名患者达到了 HB VI 级的结果。在 83 例接受类固醇治疗的患者中,67%的患者达到了 HB I 级的结果,30%的患者达到了 HB II-V 级的结果,没有患者达到 HB VI 级的结果。在 340 例接受手术治疗的患者中,23%的患者术后达到了 HB I 级的结果,58%的患者被评为 HB II-V 级的结果,9%的患者术后达到了 HB 级 VI 级的结果。没有任何部分瘫痪的患者达到 HB VI 级的结果。

结论

对于这种临床实体,手术与非手术干预的作用仍不确定。4 级证据研究占主导地位,但由于结局测量的描述不佳和数据报告不完整,进一步受到阻碍。没有进行正式荟萃分析的探索性汇总数据表明,需要将任何干预措施与自然愈合过程进行比较,而总体来看,自然愈合过程似乎是有利的。

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