Amram-Benamran M-L, Cochet S, Petignat P, Sappino A-P
Service d'oncologie, HUG, Geneva.
Rev Med Suisse. 2010 May 26;6(250):1062, 1064, 1066-8.
Ovarian cancer accounts for a minority of female cancers but remains the leading cause of death from gynaecologic cancers and the fifth leading cause of all cancer-related deaths among women. More than two thirds of cases of ovarian cancer are diagnosed once the disease becomes symptomatic, i.e. at an advanced stage. Though early detection constitutes a legitimate aim, no screening approach has yet been shown to reduce ovarian cancer mortality. In particular, ovarian imagery with endovaginal ultrasonography and serum tumor markers (CA-125) dosage performed in asymptomatic individuals have not proven their efficacy. Screening of asymptomatic women is not therefore recommended because of the limited prevalence of ovarian cancer in the general population.
卵巢癌在女性癌症中占比少数，但仍是妇科癌症死亡的主要原因，也是女性所有癌症相关死亡的第五大原因。超过三分之二的卵巢癌病例在出现症状时才被诊断出来，即处于晚期。尽管早期检测是一个合理的目标，但尚未有筛查方法被证明能降低卵巢癌死亡率。特别是，对无症状个体进行经阴道超声卵巢成像和血清肿瘤标志物（CA-125）检测尚未证明其有效性。因此，由于卵巢癌在普通人群中的患病率有限，不建议对无症状女性进行筛查。
