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台湾眼镜蛇(眼镜蛇)毒液中具有主要融合活性的心脏毒素V的初步晶体学分析。

Preliminary crystallographic analysis of cardiotoxin V with major fusion activity from Taiwan cobra (Naja naja atra) venom.

作者信息

Chen C J, Rose J, Hsiao C D, Lee T J, Wu W G, Wang B C

机构信息

Department of Crystallography, University of Pittsburgh, PA 15260.

出版信息

J Mol Biol. 1991 Jun 20;219(4):591-2. doi: 10.1016/0022-2836(91)90653-n.

DOI:10.1016/0022-2836(91)90653-n
PMID:2056526
Abstract

Crystals of a cardiotoxin from Taiwan cobra venom have been obtained by the vapor diffusion method using methyl pentanediol as precipitant. The crystals belong to the hexagonal space group P6(1)22 (or P6(5)22), with cell dimensions a = b = 47.5 A, c = 111.3 A, alpha = beta = 90 degrees and gamma = 120 degrees and diffract to a resolution of 2.2 A. There is one molecule per asymmetric unit and the solvent content is estimated to be 53%.

摘要

利用甲基戊二醇作为沉淀剂,通过气相扩散法获得了台湾眼镜蛇毒心脏毒素的晶体。这些晶体属于六方空间群P6(1)22(或P6(5)22),晶胞参数为a = b = 47.5 Å,c = 111.3 Å,α = β = 90°,γ = 120°,衍射分辨率为2.2 Å。每个不对称单元中有一个分子,溶剂含量估计为53%。

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