Amris Kirstine, Jespersen Anders
Parker Instituttet og Reumatologisk Afdeling H, Frederiksberg Hospital, 2000 Frederiksberg, Denmark.
Ugeskr Laeger. 2010 Jun 14;172(24):1832-5.
Fibromyalgia is characterised by chronic widespread pain and mechanical hyperalgesia. It is associated with a higher pain intensity, fewer pain-free intervals and more pronounced pain-related interference in function than other musculoskeletal pain conditions. Increasing evidence supports an underlying augmented central pain processing which includes sensitization of pain-transmitting neurons and dysfunction of pain inhibitory pathways. If this permanent change in the function of the nociceptive system is shown to equal fibromyalgia, the condition may be considered a neuropathic pain condition.
纤维肌痛的特征是慢性广泛性疼痛和机械性痛觉过敏。与其他肌肉骨骼疼痛状况相比，它具有更高的疼痛强度、更少的无痛间歇期以及更明显的与疼痛相关的功能障碍。越来越多的证据支持存在潜在的中枢性疼痛处理增强，这包括疼痛传递神经元的敏化和疼痛抑制通路的功能障碍。如果伤害感受系统功能的这种永久性变化被证明等同于纤维肌痛，那么该病症可能被视为一种神经性疼痛病症。
