早期乳腺癌治疗后性问题的流行情况及其相关因素：一项法国探索性调查的结果。

Prevalence and associated factors of sexual problems after early-stage breast cancer treatment: results of a French exploratory survey.

机构信息

Psycho-Oncology Unit, Supportive Care Department, Institut Curie, Paris, France.

出版信息

Psychooncology. 2011 Aug;20(8):841-50. doi: 10.1002/pon.1789. Epub 2010 Jun 21.

DOI:10.1002/pon.1789

PMID:20568085

Abstract

OBJECTIVE

The objective of this study was to assess the prevalence and associated factors of sexual activity, sexual problems or sexual satisfaction in French early-stage breast cancer survivors (BCS).

METHODS

Eight hundred and fifty eligible, post-treatment (6 months-5 years) female patients, aged 18-70 years, randomly selected from a consultation list, were invited to fill in questionnaires exploring quality of life (EORTC QLQ-C30 and QLQ-BR23), body image scale, and sexuality (Sexual Activity Questionnaire-SAQ; Relationship and Sexuality Scale; French Sexual Behaviour Survey-CSF).

RESULTS

Fifty-three percent of BCS agreed to participate. Participating women (n=378) were younger, more often premenopausal at diagnosis and with a more recent diagnosis than non-respondents. The prevalence of sexual problems was significantly higher in BCS compared with adjusted data from a French female representative sample (p<0.0001). In logistic regression, no sexual activity (R(2) =0.37) or sexual dissatisfaction (R(2) =0.28) were associated with the feeling of emotional separation in the couple or of partner's fear of sexual intercourse, lower emotional functioning, poorer body image, or co-morbidities. In sexually active women (71% of respondents), lower frequency of sexual activity (R(2) =0.26), lower sexual pleasure (R(2) =0.22), or higher sexual discomfort (R(2) =0.22) were associated with the feeling of emotional separation in the couple or of partner's fear of sexual intercourse, lower emotional functioning, age (>50 years), nausea, or insomnia (all Hosmer-Lemeshow tests: p=NS).

CONCLUSIONS

Psychological factors including the perception of the couple relationship appeared prominent in BCS women's experience of sexual problems.

摘要

目的

本研究旨在评估法国早期乳腺癌幸存者（BCS）的性行为、性问题或性满意度的流行情况及相关因素。

方法

从咨询名单中随机抽取 850 名符合条件的、治疗后（6 个月至 5 年）的 18-70 岁女性患者，邀请她们填写调查问卷，以评估生活质量（EORTC QLQ-C30 和 QLQ-BR23）、身体意象量表和性行为（性活动问卷-SAQ；关系和性量表；法国性行为调查-CSF）。

结果

53%的 BCS 同意参与。与未回复者相比，参与的女性（n=378）年龄更小，绝经前诊断的比例更高，诊断时间更新。与法国女性代表性样本的调整数据相比，BCS 中性问题的发生率显著更高（p<0.0001）。在逻辑回归中，没有性行为（R(2) =0.37）或性不满意（R(2) =0.28）与夫妻之间的情感分离感或伴侣对性的恐惧、较低的情绪功能、较差的身体意象或合并症相关。在有性行为的女性中（71%的受访者），较低的性行为频率（R(2) =0.26）、较低的性快感（R(2) =0.22）或较高的性不适（R(2) =0.22）与夫妻之间的情感分离感或伴侣对性的恐惧、较低的情绪功能、年龄（>50 岁）、恶心或失眠（所有 Hosmer-Lemeshow 检验：p=NS）相关。