Lominadze D G, Mchedlishvili G I
Patol Fiziol Eksp Ter. 1991 Jan-Feb(1):36-7.
The experiments were carried out with a special "biological model" in which the rabbits' red blood cell suspension possessing low hematocrit circulated in frogs' mesenterial microvessels. Red blood cell behaviour was investigated in microvessels of 19-45 microns in diameter under conditions of arbitrarily changed flow velocity in mesenterial microvessels. Automatic frame-to-frame analysis of cinematographic films with the texture analysis system (Ernst Leitz, FRG) showed that the velocity fluctuations of individual red blood cells and their radial displacements increased significantly, while their velocity profile became blunt, during slowing-down of flow from 0.7 to 0.2 mm/s. Thus the normal blood flow structure in microvessels becomes disordered under ischemic conditions entailing disturbance of blood rheological properties and creating additionally increased resistance in the vessels.
实验是在一种特殊的“生物模型”上进行的，其中具有低血细胞比容的兔红细胞悬液在蛙肠系膜微血管中循环。在肠系膜微血管中流速任意改变的条件下，研究了直径为19 - 45微米的微血管中红细胞的行为。使用纹理分析系统（德国恩斯特·莱茨公司）对电影胶片进行逐帧自动分析表明，当流速从0.7毫米/秒减慢到0.2毫米/秒时，单个红细胞的速度波动及其径向位移显著增加，而其速度分布变得平缓。因此，在缺血条件下，微血管中的正常血流结构会紊乱，这会导致血液流变学特性受到干扰，并使血管阻力额外增加。
