Dziubek Melvin, Pierrakos Charalampos, Chebli Louis, Demanet Helene, Sanoussi Ahmed, Wauthy Pierre
Department of Cardiac Surgery, Brugmann University Hospital, Universite Libre de Bruxelles, Bruxelles, Belgium.
Department of Intensive Care, Brugmann University Hospital, Universite Libre de Bruxelles, Bruxelles, Belgium.
Curr Cardiol Rev. 2018 Mar 14;14(1):15-24. doi: 10.2174/1573403X13666171110110344.
Mitral para-prosthetic leaks are rare but major complications of mitral heart valve replacements. When they must be re-operated, they are burdened with high mortality rates. We proposed to review our surgical experience in terms of approach and type of operation carried out.
Demographic, preoperative, intraoperative and postoperative characteristics of 34 patients benefited from a surgical treatment of mitral paravalvular leak, at the Brugmann University Hospital between 1996 and 2016, have been analysed retrospectively. We analysed the data to identify the risk factors of postoperative mortality. We then compared the data depending on the approach and the type of surgical treatment in order to compare the morbidity-mortality.
The postoperative mortality rate was 11.7%. The presence of endocarditis and increase in lactate dehydrogenase were predictive factors of mortality. Cardiac complications and acute kidney failure were significantly more common in the decease population. Direct mitral paravalvular leak suturing was more frequently performed on early apparition, anterior and isolated leaks, whereas a mitral heart valve replacement was most often performed to cure active primary endocarditis. The incidence of complications and mortality rates were identical according to the approach and the type of operation performed. A mitral para-prosthetic leak recurrence was observed in 33% of the cases.
Surgical treatment of mitral para-prosthetic leaks is accompanied by a high mortality rate. The operative strategy plays a major role and can influence the morbidity-mortality encountered in those patients.
二尖瓣人工瓣膜旁漏虽罕见,但却是二尖瓣心脏瓣膜置换术的主要并发症。当必须再次手术时,死亡率很高。我们建议回顾我们在手术方法和实施的手术类型方面的外科经验。
回顾性分析了1996年至2016年期间在布鲁格曼大学医院接受二尖瓣人工瓣膜旁漏手术治疗的34例患者的人口统计学、术前、术中和术后特征。我们分析数据以确定术后死亡的危险因素。然后根据手术方法和手术治疗类型比较数据,以比较发病率和死亡率。
术后死亡率为11.7%。心内膜炎的存在和乳酸脱氢酶的升高是死亡的预测因素。心脏并发症和急性肾衰竭在死亡人群中明显更为常见。直接二尖瓣人工瓣膜旁漏缝合术更常用于早期出现的、前部的和孤立的漏,而二尖瓣心脏瓣膜置换术最常用于治疗活动性原发性心内膜炎。根据手术方法和所实施的手术类型,并发症发生率和死亡率相同。33%的病例观察到二尖瓣人工瓣膜旁漏复发。
二尖瓣人工瓣膜旁漏的手术治疗伴随着高死亡率。手术策略起着主要作用,并且可以影响这些患者所遇到的发病率和死亡率。