Vakhrusheva L L, Kniazev Iu A, Martynova M I, Pirogova L B
Pediatriia. 1991(2):18-22.
The follow-up of children and adolescents (n-41) suffering from insulin-dependent diabetes mellitus has demonstrated that the increase of the thromboxane/prostacyclin ratio pointing to the derangement of microcirculatory regulation occurs during the decompensation phase of the disease and is a risk factor of the development of diabetic complications. The revealed disorders of arachidonic acid metabolism may be one of the causes of the tendency towards decrease of pulse arterial pressure in grave diabetes mellitus.
对41名胰岛素依赖型糖尿病儿童和青少年的随访表明，血栓素/前列环素比值升高表明微循环调节紊乱，这一现象出现在疾病失代偿期，是糖尿病并发症发生的一个危险因素。所发现的花生四烯酸代谢紊乱可能是重度糖尿病患者动脉脉压降低趋势的原因之一。
