Turkina T I, Marchenko L F, Pozniak T I, Kiseleva E V, Martynova M I, Lisitsyn D M
Pediatriia. 1991(2):22-5.
The determination of unsaturation of lipids contained by the blood serum and cell plasma membranes, which depends on the total amount of double bonds (DB) in unsaturated fatty acids is a new and promising method of estimating lipid metabolism in diabetes mellitus. Unsaturation was determined by ozonization. 91 children aged 7 to 15 years were examined. The control group included 10 healthy children of the same age. The standardized values of unsaturation were delimited in the healthy children, which amounted to 260 +/- 20 conventional units. A relationship was discovered between DB and the degree of compensation together with the disease standing. Comparative analysis of blood DB and the lipid spectrum demonstrated that the high values of unsaturation correlate with elevated concentrations of free cholesterol, nonesterified fatty acids, cholesterol esters, pre-beta-LP, beta-LP and triglycerides.
血清和细胞质膜所含脂质不饱和度的测定取决于不饱和脂肪酸中双键（DB）的总量，这是一种评估糖尿病脂质代谢的新的有前景的方法。不饱和度通过臭氧化法测定。对91名7至15岁的儿童进行了检查。对照组包括10名同龄健康儿童。在健康儿童中确定了不饱和度的标准化值，为260±20常规单位。发现双键数量与代偿程度以及疾病状况之间存在关联。血液双键数量与脂质谱的比较分析表明，高不饱和度值与游离胆固醇、非酯化脂肪酸、胆固醇酯、前β脂蛋白、β脂蛋白和甘油三酯浓度升高相关。
