Li Zhanjun, Xue Peifeng, Xie Hongxia, Li Xiaojuan, Xie Min
School of Pharmacy, Inner Mongolia Medical College, Hohhot 010059, China.
Zhongguo Zhong Yao Za Zhi. 2010 Apr;35(7):865-8. doi: 10.4268/cjcmm20100713.
To investigate the chemical constituents in the leaves and branches of Myricaria alopecuroides.
Solvent extraction method was employed to extract and partition. The chemical constituents were isolated by column chromatography on silica gel, Sephadex LH-20, highly porous resin HP-20. The structures of the compounds were elucidated on the basis of physiochemical properties and spectral analysis.
Eleven compounds were isolated from this plant and identified as ellagic acid 3,3',4-trimethylether (1), ellagic acid 3,3'-dimethylether (2), isorhamnetin (3), kaempferol (4), 3, 5-dihydroxy-4-methoxybenzoic acid (5), daucosterol (6), 6,7,10-trihydroxy-8-octadecenoic acid (7), quercetin (8), gallic acid (9), palmitic acid (10), hexadecanoic acid, 2,3-dihydroxypropyl ester (11).
Except 8 and 9, all compounds were isolated from M. alopecuroides for the first time. Compound 1, 2, 5, 7, 10, 11 were obtained from the genus Myricaria for the frist time.
研究水柏枝的叶和枝中的化学成分。
采用溶剂萃取法进行提取和分离。通过硅胶柱色谱、葡聚糖凝胶LH - 20柱色谱、大孔树脂HP - 20柱色谱对化学成分进行分离。根据化合物的理化性质和光谱分析确定其结构。
从该植物中分离得到11个化合物,分别鉴定为鞣花酸3,3',4 - 三甲醚(1)、鞣花酸3,3'-二甲醚(2)、异鼠李素(3)、山柰酚(4)、3,5 - 二羟基 - 4 - 甲氧基苯甲酸(5)、胡萝卜苷(6)、6,7,10 - 三羟基 - 8 - 十八碳烯酸(7)、槲皮素(8)、没食子酸(9)、棕榈酸(10)、十六烷酸2,3 - 二羟基丙酯(11)。
除8和9外,其余化合物均为首次从水柏枝中分离得到。化合物1、2、5、7、10、11为首次从水柏枝属植物中获得。