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Cholesterol and triglycerides in antipsychotic-naive patients with nonaffective psychosis.抗精神病药初治非情感性精神病患者的胆固醇和甘油三酯。
Psychiatry Res. 2010 Aug 15;178(3):559-61. doi: 10.1016/j.psychres.2010.06.001. Epub 2010 Jun 23.
2
Parameters of glucose and lipid metabolism at the fasted state in drug-naïve first-episode patients with psychosis: Evidence for insulin resistance.空腹状态下药物初治首发精神病患者的糖脂代谢参数：胰岛素抵抗的证据。
Psychiatry Res. 2015 Oct 30;229(3):901-4. doi: 10.1016/j.psychres.2015.07.041. Epub 2015 Aug 7.
3
Effects of antipsychotic medications in glucose and lipid metabolism at the fasted state in drug-naïve first episode patients with psychosis after six months and three years of treatment.抗精神病药物对初发精神病患者空腹血糖和血脂代谢的影响：治疗 6 个月和 3 年后的变化。
Psychiatriki. 2024 Oct 8;35(3):187-198. doi: 10.22365/jpsych.2024.008. Epub 2024 May 29.
4
Hyperlipidemia in persons using antipsychotic medication: a general population-based birth cohort study.使用抗精神病药物人群中的高脂血症：一项基于普通人群的出生队列研究。
J Clin Psychiatry. 2004 Apr;65(4):547-50. doi: 10.4088/jcp.v65n0415.
5
Increase in serum HDL level is associated with less negative symptoms after one year of antipsychotic treatment in first-episode psychosis.血清高密度脂蛋白水平升高与首发精神病患者抗精神病治疗 1 年后阴性症状减轻相关。
Schizophr Res. 2018 Jul;197:253-260. doi: 10.1016/j.schres.2017.10.042. Epub 2017 Nov 10.
6
Prolactin concentrations in newly diagnosed, antipsychotic-naïve patients with nonaffective psychosis.新诊断、抗精神病药初治的非情感性精神病患者的催乳素浓度。
Schizophr Res. 2012 Jan;134(1):16-9. doi: 10.1016/j.schres.2011.07.025. Epub 2011 Aug 9.
7
Hyperprolactinemia and insulin resistance in drug naive patients with early onset first episode psychosis.初发早发性精神分裂症患者未经药物治疗时的高催乳素血症和胰岛素抵抗。
BMC Psychiatry. 2018 Aug 1;18(1):246. doi: 10.1186/s12888-018-1827-3.
8
Is abnormal glucose tolerance in antipsychotic-naive patients with nonaffective psychosis confounded by poor health habits?抗精神病药初治非情感性精神病患者的葡萄糖耐量异常是否与不良健康习惯有关？
Schizophr Bull. 2012 Mar;38(2):280-4. doi: 10.1093/schbul/sbq058. Epub 2010 Jun 17.
9
Testosterone in newly diagnosed, antipsychotic-naive men with nonaffective psychosis: a test of the accelerated aging hypothesis.首发未使用抗精神病药物的非情感性精神病男性患者的睾酮：加速老化假说的检验。
Psychosom Med. 2011 Oct;73(8):643-7. doi: 10.1097/PSY.0b013e318230343f. Epub 2011 Sep 23.
10
Inflammatory markers in antipsychotic-naïve patients with nonaffective psychosis and deficit vs. nondeficit features.抗精神病药物治疗初发的非情感性精神病患者中伴有和不伴有缺陷症状的炎症标志物。
Psychiatry Res. 2012 Jul 30;198(2):212-5. doi: 10.1016/j.psychres.2011.08.014. Epub 2012 Mar 8.

引用本文的文献

1
Cholesterol and triglyceride levels in first-episode psychosis: systematic review and meta-analysis.首发精神病患者的胆固醇和甘油三酯水平：系统评价和荟萃分析。
Br J Psychiatry. 2017 Dec;211(6):339-349. doi: 10.1192/bjp.bp.117.200907. Epub 2017 Oct 5.

本文引用的文献

1
Metabolic risk factors in drug-naive patients with first-episode psychosis.初发精神病未用药患者的代谢风险因素
J Clin Psychiatry. 2009 Jul;70(7):997-1000. doi: 10.4088/JCP.08m04508. Epub 2009 Jun 2.
2
Metabolic profile of antipsychotic-naive individuals with non-affective psychosis.未服用抗精神病药物的非情感性精神病患者的代谢特征。
Br J Psychiatry. 2009 May;194(5):434-8. doi: 10.1192/bjp.bp.108.052605.
3
Telomere length and pulse pressure in newly diagnosed, antipsychotic-naive patients with nonaffective psychosis.新诊断的、未使用过抗精神病药物的非情感性精神病患者的端粒长度与脉压
Schizophr Bull. 2009 Mar;35(2):437-42. doi: 10.1093/schbul/sbn169. Epub 2009 Mar 11.
4
Type 2 diabetes among persons with schizophrenia and other psychotic disorders in a general population survey.一项普通人群调查中精神分裂症及其他精神障碍患者的2型糖尿病情况。
Eur Arch Psychiatry Clin Neurosci. 2008 Apr;258(3):129-36. doi: 10.1007/s00406-007-0762-y.
5
A systematic review of mortality in schizophrenia: is the differential mortality gap worsening over time?精神分裂症死亡率的系统评价：不同死亡率差距是否随时间推移而恶化？
Arch Gen Psychiatry. 2007 Oct;64(10):1123-31. doi: 10.1001/archpsyc.64.10.1123.
6
Metabolic side effects of antipsychotic medication.抗精神病药物的代谢副作用。
Int J Clin Pract. 2007 Aug;61(8):1356-70. doi: 10.1111/j.1742-1241.2007.01416.x.
7
Antipsychotic medications: metabolic and cardiovascular risk.抗精神病药物：代谢和心血管风险。
J Clin Psychiatry. 2007;68 Suppl 4:8-13.
8
Hyperlipidemia following treatment with antipsychotic medications.抗精神病药物治疗后出现的高脂血症。
Am J Psychiatry. 2006 Oct;163(10):1821-5. doi: 10.1176/ajp.2006.163.10.1821.
9
The effects of antipsychotic therapy on serum lipids: a comprehensive review.抗精神病药物治疗对血脂的影响：一项全面综述。
Schizophr Res. 2004 Sep 1;70(1):1-17. doi: 10.1016/j.schres.2004.01.014.
10
Impaired fasting glucose tolerance in first-episode, drug-naive patients with schizophrenia.首发、未用药的精神分裂症患者空腹血糖耐量受损。
Am J Psychiatry. 2003 Feb;160(2):284-9. doi: 10.1176/appi.ajp.160.2.284.

抗精神病药初治非情感性精神病患者的胆固醇和甘油三酯。

Cholesterol and triglycerides in antipsychotic-naive patients with nonaffective psychosis.

机构信息

Department of Psychiatry, Texas A&M College of Medicine, Scott & White Healthcare, Temple, TX 76508, United States.

出版信息

Psychiatry Res. 2010 Aug 15;178(3):559-61. doi: 10.1016/j.psychres.2010.06.001. Epub 2010 Jun 23.

DOI:10.1016/j.psychres.2010.06.001
PMID:20576293
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4185193/
Abstract

Patients with psychosis have an increased prevalence of hyperlipidemia. We compared fasting concentrations of lipids in newly diagnosed, antipsychotic-naïve patients with nonaffective psychosis (N=87) and control subjects (N=92). After accounting for gender, age, smoking, socioeconomic status, and body mass index, there was no significant difference between the two groups in total cholesterol, high-density lipoproteins, low-density lipoproteins, or triglycerides.

摘要

精神病患者的高血脂患病率较高。我们比较了初诊、未经抗精神病药物治疗的精神病（N=87）和对照组（N=92）患者的空腹血脂浓度。在考虑了性别、年龄、吸烟、社会经济地位和体重指数后，两组间的总胆固醇、高密度脂蛋白、低密度脂蛋白或甘油三酯均无显著差异。