Bioorganic Chemistry Lab, Department of Chemistry, Inha University, 253 Younghyun-Dong, Nam-Gu, Inchon-City 402-751, Republic of Korea.
Analyst. 2010 Aug;135(8):2079-84. doi: 10.1039/c0an00059k. Epub 2010 Jun 25.
We developed a simple dual signal (color and 'Off-On' fluorescent change) ensemble system based on the complex between a rhodamine derivative 1 and Al(3+) for the detection of pyrophosphate (PPi) in 100% aqueous solutions. The complex between the rhodamine compound and Al(3+) was utilized as a chemosensing ensemble for the first time. The ensemble showed highly sensitive and selective fluorescent and colorimetric response to pyrophosphate among the anions in 100% aqueous solutions and no interference of the potent biological competitors including ATP, ADP, and phosphate for the detection of PPi in 100% aqueous solutions at pH 7.4.
我们开发了一种简单的双重信号（颜色和“关-开”荧光变化）整体系统，该系统基于罗丹明衍生物 1 与 Al(3+) 的复合物，用于在 100%水溶液中检测焦磷酸根（PPi）。罗丹明化合物与 Al(3+) 的复合物首次被用作化学感应整体。该整体在 100%水溶液中的阴离子中对焦磷酸根表现出高度灵敏和选择性的荧光和比色响应，并且在 pH 7.4 的 100%水溶液中检测 PPi 时，没有包括 ATP、ADP 和磷酸盐在内的强生物竞争物的干扰。
