Baerlocher Gabriela M, Oppliger Leibundgut Elisabeth
Universitätsklinik für Hämatologie und Hämatologisches Zentrallabor, Inselspital Bern.
Ther Umsch. 2010 Jul;67(7):349-58. doi: 10.1024/0040-5930/a000063.
During the last 10 years several molecular markers have been established as useful tools among the armamentarium of a hematologist. As a consequence, the number of performed hematologic molecular analyses has immensely increased. Often, such tests replace or complement other laboratory methods. Molecular markers can be useful in many ways: they can serve for diagnostics, describe the prognostic profile, predict which types of drugs are indicated, and can be used for the therapeutic monitoring of the patient to indicate an adequate response or predict resistance or relapse of the disease. Many markers fulfill more than one of these aspects. Most important, however, is the right choice of analyses at the right time-points!
在过去十年中，几种分子标志物已成为血液科医生众多工具中的有用手段。因此，血液学分子分析的执行数量大幅增加。通常，此类检测可替代或补充其他实验室方法。分子标志物在许多方面都很有用：它们可用于诊断、描述预后情况、预测适用的药物类型，还可用于对患者进行治疗监测，以表明是否有足够的反应或预测疾病的耐药性或复发情况。许多标志物能满足不止一个方面的需求。然而，最重要的是在正确的时间点做出正确的分析选择！
