Department of Clinical Bacteriology and Mycology, Kimron Veterinary Institute, PO Box 12, Bet-Dagan 50250, Israel.
Vet J. 2011 Jan;187(1):33-41. doi: 10.1016/j.tvjl.2010.05.028. Epub 2010 Jun 26.
Fungi belonging to the Scedosporium/Pseudallescheria complex (SPCF) have been known to cause human infections for nearly a century and are important human pathogens, with an increasing frequency of infection in patients with underlying conditions. There appears to be a lower incidence of infections with SPCF in veterinary species, although this may be related to a lack of awareness of these diseases. Important recent taxonomic changes in this group of fungi include the classification of Pseudallescheria boydii and Scedosporium apiospermum as two distinct species and the identification of new pathogenic species of SPCF. In this article, the literature on natural and experimental infections caused by SPCF in veterinary species is reviewed. The importance of an accurate identification of veterinary isolates by molecular methods is stressed, especially since virulence and susceptibility to antimycotic drugs of different species may vary.
半知菌/拟青霉复合体(SPCF)真菌近一个世纪以来一直被认为可引起人类感染,是重要的人类病原体,在基础疾病患者中的感染频率不断增加。兽医物种的 SPCF 感染似乎发生率较低,尽管这可能与对这些疾病缺乏认识有关。该真菌群的重要近期分类学变化包括将拟青霉属和枝顶孢属鉴定为两个不同的种,以及鉴定 SPCF 的新致病性种。本文综述了 SPCF 在兽医物种中引起的自然和实验感染的文献。强调了通过分子方法准确鉴定兽医分离株的重要性,特别是因为不同种的毒力和对抗真菌药物的敏感性可能不同。