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拟青霉/枝顶孢属复合种:从腐生真菌到致病性真菌。

Pseudallescheria/Scedosporium complex species: From saprobic to pathogenic fungus.

机构信息

Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, 10400 Bangkok, Thailand.

出版信息

J Mycol Med. 2018 Jun;28(2):249-256. doi: 10.1016/j.mycmed.2018.02.015. Epub 2018 Mar 19.

DOI:10.1016/j.mycmed.2018.02.015
PMID:29567285
Abstract

Scedosporiosis is an emerging fungal infection caused by Pseudallescheria/Scedosporium complex species (PSC). This pathogen has been drawn significant interest in recent years due to its worldwide prevalence, the seriousness of its infection, associated with high mortality in both immunocompromised and immunocompetent hosts and its cryptic ecology, distribution and epidemiology across the globe. These species complexes can be found in environments impacted by human. The purpose of this review is to describe the characteristics, mode of transmission, ecology, prevalence, global epidemiology of this fungal group in order to increase the awareness of among clinicians and microbiologists, especially in regions with high endemic, as well as to promote further research on all of its aspects.

摘要

枝孢霉病是一种由拟青霉/枝孢霉复合体(PSC)引起的新兴真菌感染。近年来,由于其在全球范围内的流行、感染的严重性,以及在免疫功能低下和免疫功能正常宿主中都与高死亡率相关,再加上其在全球范围内隐匿的生态、分布和流行病学特征,这种病原体引起了人们的极大关注。这些物种复合体可以在受人类影响的环境中找到。本综述的目的是描述该真菌群的特征、传播方式、生态学、流行率和全球流行病学,以提高临床医生和微生物学家的认识,特别是在高地方性流行的地区,并促进对其所有方面的进一步研究。

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