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与尿源性 hCG 相比，重组 hCG 触发在单囊胚 IVF 拮抗剂周期中可提高出生率：一项随机对照试验。

Higher birth rate after recombinant hCG triggering compared with urinary-derived hCG in single-blastocyst IVF antagonist cycles: a randomized controlled trial.

机构信息

Center for Reproductive Medicine, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium.

出版信息

Fertil Steril. 2010 Dec;94(7):2902-4. doi: 10.1016/j.fertnstert.2010.04.077. Epub 2010 Jun 26.

DOI:10.1016/j.fertnstert.2010.04.077
PMID:20580358
Abstract

In a prospective randomized controlled trial, 119 patients were randomized to receive either recombinant hCG (250 μg) or urinary-derived hCG (10,000 IU) for final oocyte maturation in an antagonist protocol with a fixed dose of recombinant FSH (187.5 IU) and predefined single blastocyst transfer. The delivery rate was improved in the recombinant hCG group compared with the urinary-derived hCG group (44.1 vs. 25.7, respectively); however, adequately powered randomized controlled trials are justified to ascertain whether this difference is true.

摘要

在一项前瞻性随机对照试验中，119 例患者被随机分为重组 hCG（250μg）组或尿源性 hCG（10000IU）组，均采用拮抗剂方案，给予固定剂量的重组 FSH（187.5IU），并进行预设的单个囊胚移植。与尿源性 hCG 组相比，重组 hCG 组的分娩率提高（分别为 44.1%和 25.7%）；然而，需要进行充分的随机对照试验来确定这种差异是否真实。

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