Department of Chemistry, Faculty of Science and Engineering, Saga University, 1 Honjo-machi, Saga 840-8502, Japan.
J Colloid Interface Sci. 2010 Oct 1;350(1):63-8. doi: 10.1016/j.jcis.2010.06.007. Epub 2010 Jun 8.
Two distinct types of micelle structures have been successfully obtained from poly(ethylene oxide-b-methacrylic acid) (PEO-b-PMAA) in aqueous solutions: one with a PEO-core surrounded by a PMAA corona and the other with a PMAA-core surrounded by a PEO-corona. The PEO-core micelles were obtained by decreasing the cloud point of the PEO to room temperature by adding phosphate ions PO(4)(3-), and the PMAA-core micelles were obtained by reducing the solubility of the PMAA block by adding calcium ions (Ca(2+)). The reversibility between the PMAA-core and PEO-core micelles was also confirmed; (1) the transformation from the PMAA-core to PEO-core micelles was achieved by solubilizing the PMAA block by removing Ca(2+) with ethylenediaminetetraacetic acid followed by the addition of PO(4)(3-), and (2) the reverse transformation was carried out by removing PO(4)(3-) by dialysis followed by the addition of Ca(2+). The two types of micelles were characterized using various techniques such as turbidimetry, dynamic light scattering, scanning electron microscopy and electrophoretic light scattering.
已成功从聚（氧化乙烯-甲基丙烯酸）（PEO-b-PMAA）在水溶液中获得两种不同类型的胶束结构：一种是 PEO 核被 PMAA 壳包围，另一种是 PMAA 核被 PEO 壳包围。通过添加磷酸根离子 PO(4)(3-)将 PEO 的浊点降低到室温，得到 PEO 核胶束，通过添加钙离子 (Ca(2+))降低 PMAA 嵌段的溶解度，得到 PMAA 核胶束。还证实了 PMAA 核和 PEO 核胶束之间的可逆性；(1) 通过用乙二胺四乙酸（EDTA）去除 Ca(2+)溶解 PMAA 嵌段，然后加入 PO(4)(3-)，实现了从 PMAA 核到 PEO 核胶束的转变，(2) 通过透析去除 PO(4)(3-)，然后加入 Ca(2+)，进行了相反的转变。使用浊度法、动态光散射、扫描电子显微镜和电泳光散射等各种技术对两种类型的胶束进行了表征。
