立陶宛女性亚麻纺织制造工人的癌症发病率。

Institute of Oncology, Vilnius University. Baublio 3B, Vilnius, Lithuania.

Occup Environ Med. 2010 Jul;67(7):500-2. doi: 10.1136/oem.2009.048058.

OBJECTIVE

To determine site-specific cancer incidence among women spinning-weaving and dyeing-finishing workers in the largest flax textile factory in Lithuania.

METHOD

The cancer incidence of a cohort of 3447 women workers from a flax textile factory was investigated for the period 1978-2002. All subjects were employed at the plant in the period 1957-2000 for a minimum of 12 months. Standardised incidence ratios (SIRs) were estimated by use of the corresponding national rates. SIRs were calculated for the spinning-weaving and dyeing-finishing work categories, and for two durations of employment categories (<10 years, > or =10 years).

RESULTS

The cancer SIRs among spinning-weaving and dyeing-finishing workers were 0.84 (95% CI 0.69 to 1.00) and 0.90 (95% CI 0.52 to 1.44). An incidence deficit for non-melanoma skin cancer was found for the spinning-weaving unit (SIR 0.45, 95% CI 0.18 to 0.92). The risk of oral cavity and pharynx cancer was significantly increased in spinning-weaving unit workers with <10 years of employment (SIR 5.71, 95% CI 1.56 to 14.60). A significant excess of thyroid cancer and nervous system cancer was found among dyeing-finishing workers.

CONCLUSIONS

The overall cancer and non-melanoma skin cancer incidence rate among flax spinning-weaving workers was lower compared with the Lithuanian population. The present findings lend some support to an excess of thyroid and nervous system cancers among dyeing-finishing workers and of oral cavity and pharynx cancer in spinning-weaving workers.

目的

确定立陶宛最大亚麻纺织厂纺线和染整工人中特定部位癌症的发病率。

方法

调查了一家亚麻纺织厂 3447 名女工的癌症发病率，调查时间为 1978 年至 2002 年。所有研究对象均于 1957 年至 2000 年期间在工厂工作至少 12 个月。使用相应的国家发病率计算标准化发病比（SIR）。纺线和染整工作类别以及两个工作年限类别（<10 年和>=10 年）的 SIR 均进行了计算。

结果

纺线和染整工人的癌症 SIR 分别为 0.84（95%CI 0.69 至 1.00）和 0.90（95%CI 0.52 至 1.44）。纺线车间非黑色素瘤皮肤癌发病率呈下降趋势（SIR 0.45，95%CI 0.18 至 0.92）。纺线车间工作年限<10 年的工人口腔和咽部癌症风险显著增加（SIR 5.71，95%CI 1.56 至 14.60）。染整工人的甲状腺癌和神经系统癌症发病率显著升高。