Li S M, Li D, Ling F, Miao Z R, Wang M L
From the Interventional Center, Xuan-Wu Hospital, the Capital University of Medical Science, Beijing; China -
Interv Neuroradiol. 2005 Sep 30;11(3):205-12. doi: 10.1177/159101990501100302. Epub 2005 Oct 26.
Concern regarding the safety of Carotid angioplasty and stenting (CAS) exists because of the risk of cerebral embolization during the procedure. The purpose of this article is to discuss that technology modification may improve the outcomes of this procedure. Between October 1997 and October 2004, 439 consecutive patients with 478 stenotic carotid arteries were treated. 284 vessels were stented without the use of embolic protection devices and 194 vessels with protection. Among cases not using protection device, 201 arteries were stented with predilation alone, 63 with postdilation alone, six with both pre- and post-dilation, two with neither and twelve were stented with balloon expandable stents. The technical success of 100%.The combined stroke and death rate during the procedure and the 30-day follow-up at 30 days was 1.67% overall. Three (0.63%) deaths occurred; one was due to a major infarction secondary to stent breakage, and two died of massive reperfusion intracerebral haemorrhage. There were total six ischemic stroke, of the five ischemic strokes wich developed in nonprotection group, two were among 201 cases with predilation alone (0.99%), which developed after stent deployment and postprocedure, and three among 63 cases with postdilation alone (4.76%), which developed immediately after postdilation. The incidence of ischemic stroke was lower among those who were stented with predilation alone than among those who were stented with postdilation alone. This likely results from reduced intimal injury and decreased risk of embolic complications.
由于颈动脉血管成形术和支架置入术(CAS)过程中存在脑栓塞风险,人们对其安全性存在担忧。本文的目的是讨论技术改进可能会改善该手术的结果。在1997年10月至2004年10月期间,对439例连续患者的478条狭窄颈动脉进行了治疗。284条血管在未使用栓子保护装置的情况下进行了支架置入,194条血管使用了保护装置。在未使用保护装置的病例中,201条动脉仅进行了预扩张后置入支架,63条仅进行了后扩张,6条同时进行了预扩张和后扩张,2条两者均未进行,12条使用球囊扩张支架进行了置入。技术成功率为100%。手术过程中和30天随访期间的综合卒中与死亡率在30天时总体为1.67%。发生了3例(0.63%)死亡;1例死于支架断裂继发的大面积梗死,2例死于大量再灌注性脑出血。共有6例缺血性卒中,在非保护组发生的5例缺血性卒中中,2例发生在仅进行预扩张的201例患者中(0.99%),发生在支架置入后及术后,3例发生在仅进行后扩张的63例患者中(4.76%),发生在后扩张后立即出现。仅进行预扩张置入支架的患者中缺血性卒中的发生率低于仅进行后扩张置入支架的患者。这可能是由于内膜损伤减少和栓塞并发症风险降低所致。