Department of Anesthesiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, 197#, No. 2 Ruijin Road, Shanghai 200025, P. R. China.
Anesth Analg. 2010 Aug;111(2):417-20. doi: 10.1213/ANE.0b013e3181e30b54. Epub 2010 Jun 28.
There may be large differences between measurements of end-tidal carbon dioxide partial pressure (Petco(2)) and arterial carbon dioxide partial pressure (Paco(2)) during laparoscopic surgeries. Transcutaneous carbon dioxide (Ptcco(2)) monitoring can be used to noninvasively and continuously estimate Paco(2). In the present study we evaluated the accuracy of Ptcco(2) monitoring in predicting the Paco(2) during laparoscopic surgeries with prolonged pneumoperitoneum.
Sixteen patients who underwent laparoscopic radical gastrectomy or radical proctectomy under general anesthesia were included in the study. Their Paco(2), Petco(2), and Ptcco(2) values were measured at 3 time points before and after pneumoperitoneum. Agreement among measures was assessed by the Bland-Altman method.
Forty-eight sample sets were obtained. The average Paco(2)- Ptcco(2) difference was -0.9 + or - 6.4 mm Hg (mean + or - 2 SD). The average Paco(2) - Petco(2) difference was 7.5 + or - 7.0 mm Hg (mean + or - 2 SD). Paco(2) - Ptcco(2) was less than or equal to + or -5 mm Hg for 88% of the samples. Paco(2) - Petco(2) was less than or equal to + or -5 mm Hg for 17% of the samples (P < 0.05).
While undergoing long-term pneumoperitoneum laparoscopic surgery, Ptcco(2) monitoring is more accurate than is PETCO(2) monitoring in predicting the patients' Paco(2).
在腹腔镜手术中,呼气末二氧化碳分压(Petco(2))和动脉二氧化碳分压(Paco(2))的测量值可能存在很大差异。经皮二氧化碳(Ptcco(2))监测可用于无创且连续地估计 Paco(2)。在本研究中,我们评估了经皮二氧化碳监测在预测长时间气腹腹腔镜手术中 Paco(2)时的准确性。
本研究纳入了 16 例在全身麻醉下接受腹腔镜根治性胃切除术或根治性直肠切除术的患者。在气腹前后的 3 个时间点测量了他们的 Paco(2)、Petco(2)和 Ptcco(2)值。采用 Bland-Altman 法评估各指标之间的一致性。
共获得 48 组样本。Paco(2) - Ptcco(2)差值的平均值为-0.9 ± 6.4mmHg(平均±2SD)。Paco(2) - Petco(2)差值的平均值为 7.5 ± 7.0mmHg(平均±2SD)。88%的样本中 Paco(2) - Ptcco(2)差值≤±5mmHg。17%的样本中 Paco(2) - Petco(2)差值≤±5mmHg(P<0.05)。
在进行长时间气腹腹腔镜手术时,Ptcco(2)监测在预测患者 Paco(2)方面比 PETCO(2)监测更准确。