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山羊肱骨中的软骨肉瘤。

Chondrosarcoma in the humerus of a goat.

作者信息

Schmid T, Hilbe M, Ohlert S, Nuss K

机构信息

Department of Farm Animals, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland.

出版信息

Vet Comp Orthop Traumatol. 2010;23(4):273-6. doi: 10.3415/VCOT-09-11-0116. Epub 2010 Jun 21.

Abstract

The clinical, radiographical and histo-pathological findings of a chondrosarcoma in the humerus of a goat are discussed. An 11-year-old female Saanen goat was admitted for evaluation of chronic, progressive left forelimb lameness. Clinical examination revealed signs of pain in the shoulder region. Radiographs of the scapulohumeral joint showed a large lytic lesion of the proximal third of the humerus with cortical destruction, intralesional calcification and marked periosteal reactions. Differential diagnoses included aggressive bone lesions as seen with osteomyelitis or a primary bone tumour, such as osteosarcoma, chondrosarcoma or fibrosarcoma. The goat was euthanatized for humane reasons because of the poor prognosis. On the basis of the histopathological findings, the lesion was diagnosed as grade II chondrosarcoma. The tumour had already spread to the lungs and the left prescapular lymph node at the time of diagnosis.

摘要

本文讨论了一只山羊肱骨软骨肉瘤的临床、影像学和组织病理学检查结果。一只11岁的雌性萨能山羊因慢性进行性左前肢跛行入院评估。临床检查发现肩部区域有疼痛迹象。肩胛肱骨关节的X线片显示肱骨近端三分之一处有一个大的溶骨性病变,伴有皮质破坏、病灶内钙化和明显的骨膜反应。鉴别诊断包括骨髓炎或原发性骨肿瘤(如骨肉瘤、软骨肉瘤或纤维肉瘤)所见的侵袭性骨病变。由于预后不佳,出于人道原因对该山羊实施了安乐死。根据组织病理学检查结果,该病变被诊断为II级软骨肉瘤。诊断时肿瘤已扩散至肺部和左肩胛前淋巴结。

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