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侏儒山羊的肋部间叶性软骨肉瘤伴弥漫性胸膜和心包外植

Costal mesenchymal chondrosarcoma with diffuse pleural and pericardial explantation in a pygmy goat.

作者信息

Lombardini Eric D, de la Concha Andres, Pierce Virginia, Pool Roy R

机构信息

Department of Veterinary Medicine, Armed Forces Research Institute of Medical Sciences, USAMC-AFRIMS, APO AP96546-5000, USA.

Faculty of Virology, CVM, Texas A&M Veterinary Medical Diagnostic Laboratory , 1 Sippel Road, College Station, Texas 77843, USA.

出版信息

J Toxicol Pathol. 2014 Apr;27(1):81-5. doi: 10.1293/tox.2013-0040. Epub 2014 Apr 30.

Abstract

A 3 year old intact male pygmy goat developed progressive weakness and eventual recumbancy over the course of 1 week, while maintaining its ability to eat and drink. The animal died and at necropsy, the parietal pleural surfaces and the pericardial surface were noted to be covered with firm, white, variably sized nodules that often formed linear arrays or coalesced into larger clumped aggregates. The visceral pleural surfaces of the ventral lung lobes were also covered with similar nodules. Histopathological and immunohistochemical evaluation of the submitted tissues revealed a diagnosis of mesenchymal chondrosarcoma with extensive seeding throughout the thoracic cavity.

摘要

一只3岁未阉割的雄性侏儒山羊在1周内逐渐出现进行性虚弱,最终卧地不起,但其仍能进食和饮水。该动物死亡,尸检时发现壁层胸膜表面和心包表面覆盖着坚实、白色、大小不一的结节,这些结节常形成线性排列或融合成更大的团块。腹侧肺叶的脏层胸膜表面也覆盖着类似的结节。对送检组织进行组织病理学和免疫组织化学评估后,诊断为间叶性软骨肉瘤,肿瘤细胞在胸腔内广泛播散。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fe7/4000077/d1075d52a2ea/tox-27-081-g001.jpg

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