Morukov V B, Rykova M P, Antropova E N, Berendeeva T A, Ponomarev S A, Larina I M
Fiziol Cheloveka. 2010 May-Jun;36(3):19-30.
Results of innate and adaptive immunity indicators research at 12 cosmonauts who took part in long (128-215 days) expeditions to the International space station (ISS) are presented. It is shown that a space flight can lead to deflection of deviations in human immune system. These shifts occurred in decrease of phagocytes, NK, T-lymphocytes functional activity and also in abilities of immunocompetent cells to synthesize cytokines. Significant individual changes are noted in reaction of immune system to the long term space flight conditions specifying on individual predisposition to development of immune reactance infringements in the conditions of varying gravitational influences.
本文展示了对12名参与前往国际空间站（ISS）的长期（128 - 215天）任务的宇航员进行先天和适应性免疫指标研究的结果。结果表明，太空飞行会导致人体免疫系统出现偏差。这些变化表现为吞噬细胞、自然杀伤细胞（NK）、T淋巴细胞功能活性下降，以及免疫活性细胞合成细胞因子的能力下降。免疫系统对长期太空飞行条件的反应存在显著个体差异，这表明在不同重力影响条件下，个体对免疫反应受损的易感性不同。
