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[7天干浸期间人体免疫系统状态]

[Human immunity system status during 7-day dry immersion].

作者信息

Berendeeva T A, Rykova M P, Antropova E N, Larina I M, Morukov B V

出版信息

Aviakosm Ekolog Med. 2009 Sep-Oct;43(5):36-42.

PMID:20120915
Abstract

Subpopulations of lymphocytes, activation potential of T-, B- and NK-cells as well as cytokines production by immunocompetent cells in peripheral blood were studied in five volunteers for 7-day dry immersion without use of countermeasures. Results of the investigation revealed several negative shifts in the immunity and cytokines systems instigated by the experimental conditions. The considerable variability of the immune reactions to immersion suggests individual predisposition to immunological breaks in a changed gravity environment.

摘要

在五名志愿者中研究了淋巴细胞亚群、T细胞、B细胞和NK细胞的激活潜能以及外周血中免疫活性细胞产生细胞因子的情况,这些志愿者在不采取对抗措施的情况下进行了7天的干浸试验。研究结果揭示了实验条件引发的免疫和细胞因子系统的若干负面变化。对浸没问题免疫反应的显著变异性表明个体在重力环境改变时易发生免疫紊乱。

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A dry immersion model of microgravity modulates platelet phenotype, miRNA signature, and circulating plasma protein biomarker profile.微重力的干燥浸泡模型调节血小板表型、miRNA 特征和循环血浆蛋白生物标志物谱。
Sci Rep. 2021 Nov 9;11(1):21906. doi: 10.1038/s41598-021-01335-x.
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Long-term dry immersion: review and prospects.长期干燥浸泡:综述与展望。
Eur J Appl Physiol. 2011 Jul;111(7):1235-60. doi: 10.1007/s00421-010-1750-x. Epub 2010 Dec 14.