Frieling T, Cooke H J, Wood J D
Department of Physiology, College of Medicine, Ohio State University, Columbus 43210-1238.
Am J Physiol. 1991 Jun;260(6 Pt 1):G835-41. doi: 10.1152/ajpgi.1991.260.6.G835.
Intracellular recording methods were used in vitro to study the electrophysiological behavior of neurons in ganglia of the submucosal plexus in the distal colon of the guinea pig. The results revealed subpopulations of submucosal ganglion cells that corresponded to the AH/type 2, S/type 1, type 3, and type 4 subpopulations found elsewhere in the intestine. Electrical behavior of colonic submucosal neurons differed from the myenteric plexus of the colon, rectum, and stomach and the small intestinal submucosal plexus mainly in the relative proportions of the different subpopulations. Regional differences in this respect may be a reflection of functional specialization in the diverse regions of the alimentary canal.
采用细胞内记录方法在体外研究豚鼠远端结肠黏膜下神经丛神经节中神经元的电生理行为。结果显示，黏膜下神经节细胞亚群与在肠道其他部位发现的AH/2型、S/1型、3型和4型亚群相对应。结肠黏膜下神经元的电行为与结肠、直肠和胃的肌间神经丛以及小肠黏膜下神经丛的主要区别在于不同亚群的相对比例。这方面的区域差异可能反映了消化道不同区域的功能特化。
