Eddington Helen, Kalra Philip A
Salford Royal Foundation NHS Trust, Renal Department, Vascular Research Group, Salford, M6 8HD, UK.
J Ren Care. 2010 May;36 Suppl 1:61-7. doi: 10.1111/j.1755-6686.2010.00170.x.
Chronic kidney disease-mineral bone disorder (CKD-MBD) is a multifaceted definition used to help describe the systemic derangement of mineral bone metabolism in renal disease. This was previously referred to, rather simplistically, as 'renal osteodystrophy' or 'renal bone disease'. In this review, we will try to show the evidence relating these factors to cardiovascular morbidity and mortality and give some evidence as to the mechanisms for this. The treatments used for this condition are also integral to the increased cardiovascular mortality seen in renal patients and a summary of these effects will also be covered.
慢性肾脏病-矿物质和骨异常（CKD-MBD）是一个多方面的定义，用于帮助描述肾脏疾病中矿物质和骨代谢的系统性紊乱。以前它被相当简单地称为“肾性骨营养不良”或“肾性骨病”。在本综述中，我们将试图展示将这些因素与心血管发病率和死亡率相关联的证据，并给出一些关于其机制的证据。用于这种病症的治疗方法也是导致肾病患者心血管死亡率增加的一个组成部分，这些影响的总结也将涵盖在内。
