Naval Medical Research Center, Silver Spring, Maryland, USA.
Emerg Infect Dis. 2010 Jul;16(7):1081-6. doi: 10.3201/eid1607.091885.
To determine the cause of acute febrile illnesses other than malaria in the North Eastern Province, Kenya, we investigated rickettsial infection among patients from Garissa Provincial Hospital for 23 months during 2006-2008. Nucleic acid preparations of serum from 6 (3.7%) of 163 patients were positive for rickettsial DNA as determined by a genus-specific quantitative real-time PCR and were subsequently confirmed by molecular sequencing to be positive for Rickettsia felis. The 6 febrile patients' symptoms included headache; nausea; and muscle, back, and joint pain. None of the patients had a skin rash.
为了确定肯尼亚东北部省除疟疾以外的急性发热性疾病的病因,我们在 2006 年至 2008 年期间对加里萨省立医院的 163 名患者进行了为期 23 个月的调查,以确定立克次体感染情况。通过种属特异性实时定量 PCR 检测,6 名(3.7%)血清核酸制剂呈立克次体 DNA 阳性,随后通过分子测序证实为猫立克次体阳性。6 名发热患者的症状包括头痛、恶心、肌肉、背部和关节疼痛。这些患者均没有皮疹。