2013 - 2014年孟加拉国人类、猫和猫蚤中猫立克次体的分子检测
Molecular Detection of Rickettsia felis in Humans, Cats, and Cat Fleas in Bangladesh, 2013-2014.
作者信息
Ahmed Rajib, Paul Shyamal Kumar, Hossain Muhammad Akram, Ahmed Salma, Mahmud Muhammad Chand, Nasreen Syeda Anjuman, Ferdouse Faria, Sharmi Rumana Hasan, Ahamed Farid, Ghosh Souvik, Urushibara Noriko, Aung Meiji Soe, Kobayashi Nobumichi
机构信息
1 Department of Microbiology, Mymensingh Medical College , Mymensingh, Bangladesh .
2 Department of Biochemistry, Manikganj Medical College , Manikganj, Bangladesh .
出版信息
Vector Borne Zoonotic Dis. 2016 May;16(5):356-8. doi: 10.1089/vbz.2015.1886. Epub 2016 Feb 22.
High prevalence of Rickettsia felis in patients with fever of unknown origin was revealed in the north-central Bangladesh from 2012 to 2013. Subsequently, in this study, prevalence of R. felis in cats and cat fleas (Ctenocephalides felis), together with febrile patients, was studied by PCR detection of 17 kDa antigen gene and DNA sequencing. R. felis was detected in 28% (28/100) and 21% (14/68) of cat blood and cat flea samples, respectively, whereas 42% (21/50) of patients were positive for R. felis. R. felis-positive cat fleas were detected at significantly higher rate on R. felis-positive cats. The results suggested a potential role of cats and cat fleas for transmission of R. felis to humans in Bangladesh.
2012年至2013年期间，在孟加拉国中北部地区发现不明原因发热患者中猫立克次体的高流行率。随后，在本研究中，通过PCR检测17 kDa抗原基因和DNA测序，研究了猫和猫蚤（猫栉首蚤）中猫立克次体的流行率，同时也对发热患者进行了研究。分别在28%（28/100）的猫血样本和21%（14/68）的猫蚤样本中检测到猫立克次体，而42%（21/50）的患者猫立克次体呈阳性。在猫立克次体阳性的猫身上，检测到猫立克次体阳性猫蚤的比例显著更高。结果表明，在孟加拉国，猫和猫蚤在猫立克次体传播给人类方面可能发挥了作用。
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