Ohmomo T, Kurata A, Suzuki S, Fujii K
Department of Neurosurgery, Chofu Hospital, Tokyo; Japan.
Interv Neuroradiol. 2004 Mar 30;10 Suppl 1(Suppl 1):77-82. doi: 10.1177/15910199040100S111. Epub 2008 Jun 9.
With the recent improvement of endovascular techniques, intra-arterial local fibrinolytic therapy has become widely available for treatment of acute embolic stroke and there is some evidence that it could be superior to conventional approaches (1-6). However, because of high mortality and morbidity, strokes involving the internal carotid artery (ICA) and featuring acute thromboembolic occlusion remain problematic (7). We have successfully performed intra-arterial local fibrinolytic therapy via the anterior communicating artery through the contra-lateral ICA in two consecutive cases of thromboembolic occlusion of the ICA, anterior cerebral artery (ACA) and middle cerebral artery (MCA), and obtained satisfactory results.We here present details of this new technique applied for the two cases and discuss the efficacy of this method compared with conventional approaches.
随着近年来血管内技术的改进,动脉内局部纤溶治疗已广泛应用于急性栓塞性卒中的治疗,并且有证据表明其可能优于传统方法(1-6)。然而,由于高死亡率和高发病率,累及颈内动脉(ICA)且表现为急性血栓栓塞性闭塞的卒中仍然是个难题(7)。我们成功地通过对侧ICA经前交通动脉对2例ICA、大脑前动脉(ACA)和大脑中动脉(MCA)血栓栓塞性闭塞的患者进行了动脉内局部纤溶治疗,并取得了满意的结果。在此,我们介绍应用于这2例患者的这项新技术的详细情况,并与传统方法比较讨论该方法的疗效。