Tenjin H
Department of Neurosurgery; Kyoto Prefectural Yosanoumi Hospital Kyotofu; Japan -
Interv Neuroradiol. 2004 Mar 30;10 Suppl 1(Suppl 1):153-4. doi: 10.1177/15910199040100S126. Epub 2008 Jun 9.
We investigated and compared the morphologic and haemodynamic changes between before and after stent placement when several different kinds of stents were applied to experimental aneurysms. Experimental aneurysms in eight pig carotid arteries were used. Stents were placed covering the aneurysm orifice. Five Cordis stents (coil stent), two GFXs (multilink stent), and one Multilink (tube stent) were used in this study. After stent placement, the arteries were perfused with 70% ethanol, the specimens were embedded in polyester plastic resin and thin slices were stained with hemtoxilin-eosin. Blood flow in the aneurysm was measured using digital subtraction angiography. The parent artery was stretched in multilink stent (GFX) cases, and was most markedly stretched by use of the tube stent (Multilink). Stent placement with any type of stent decreased intra-aneurysmal blood flow.
我们研究并比较了将几种不同类型的支架应用于实验性动脉瘤时，支架置入前后的形态学和血流动力学变化。使用了八只猪颈动脉的实验性动脉瘤。将支架放置在覆盖动脉瘤口处。本研究使用了五个Cordis支架（线圈支架）、两个GFX支架（多连杆支架）和一个多连杆支架（管状支架）。支架置入后，用70%乙醇灌注动脉，将标本嵌入聚酯塑料树脂中，薄片用苏木精-伊红染色。使用数字减影血管造影测量动脉瘤内的血流。在多连杆支架（GFX）病例中，母动脉被拉伸，而使用管状支架（多连杆）时拉伸最为明显。使用任何类型的支架进行支架置入都会降低动脉瘤内的血流。
