Mericle R A, Lanzino G, Wakhloo A K, Guterman L R, Hopkins L N
Department of Neurosurgery and Toshiba Stroke Research Center, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 14209-1194, USA.
Neurosurgery. 1998 Nov;43(5):1229-34. doi: 10.1097/00006123-199811000-00130.
Endovascular stents have been successfully used in the treatment of fusiform and dissecting aneurysms of the peripheral circulation and extracranial carotid and vertebral arteries. Technical limitations related to the inability to navigate the stent and the delivery system through tortuous vascular segments has limited their application with intracranial lesions. Availability of new flexible and pliable stent systems might overcome these difficulties.
A 49-year-old woman presented with a dissecting pseudoaneurysm of the horizontal portion of the petrous internal carotid artery that increased in size, as revealed by serial angiographic studies.
The aneurysm was treated by deploying a new flexible stent across the aneurysm neck and by then packing the aneurysm sac with Guglielmi detachable coils that were delivered by a microcatheter positioned through the stent struts into the aneurysm lumen.
New flexible stents can be used to treat intracranial internal carotid artery aneurysms in difficult-to-access areas, such as the horizontal petrous segment. The stent may disrupt the aneurysm inflow tract, thereby inducing stasis and facilitating intra-aneurysmal thrombosis. In addition, the stent acts as an endoluminal scaffold to prevent coil herniation into the parent artery, which allows tight packing of even wide-necked and irregularly shaped aneurysms. The stent may also serve as a matrix for endothelial growth. We think this new generation of flexible stents and the use of this described technique will usher in the next era of endovascular management of intracranial aneurysms.
血管内支架已成功用于治疗外周循环以及颅外颈动脉和椎动脉的梭形及夹层动脉瘤。由于无法使支架和输送系统通过迂曲的血管段而导致的技术限制,使得它们在颅内病变中的应用受到限制。新型柔韧性和可弯曲性支架系统的出现可能会克服这些困难。
一名49岁女性患者,经系列血管造影研究显示,其岩骨段颈内动脉水平部存在一个夹层假性动脉瘤,且动脉瘤大小增大。
通过在动脉瘤颈部部署一个新型柔韧性支架,然后用 Guglielmi 可脱性弹簧圈填充动脉瘤腔,弹簧圈通过经支架支柱置入动脉瘤腔内的微导管输送,从而治疗该动脉瘤。
新型柔韧性支架可用于治疗难以到达区域的颅内颈内动脉动脉瘤,如岩骨水平段。支架可能会破坏动脉瘤的流入道,从而导致血流淤滞并促进动脉瘤内血栓形成。此外,支架可作为腔内支架防止弹簧圈疝入载瘤动脉,这使得即使是宽颈和不规则形状的动脉瘤也能紧密填塞。支架还可作为内皮生长的基质。我们认为,新一代柔韧性支架及本文所述技术的应用将开创颅内动脉瘤血管内治疗的新纪元。