Regional coordinating centre for nosocomial infection control, Paris, France.
Euro Surveill. 2010 Jun 24;15(25):19597. doi: 10.2807/ese.15.25.19597-en.
In 2006 and 2007, a large outbreak of Clostridium difficile infections (CDIs) with PCR-ribotype 027 was identified in northern France. Overall, 38 healthcare facilities notified 529 CDIs over a 22-month period, including 281 laboratory-confirmed CDI 027 and 248 non-confirmed CDI 027 cases (incidence rate per 10,000 elective bed days: 1.63, range: 0.07 to 7.94). The cases occurred mainly in long-term care hospital facilities and nursing homes, near the border between France and Belgium. An active surveillance and prevention campaign was launched at the first epidemic peak including hygiene precautions for healthcare professionals, which supported healthcare facilities to improve care organisation. The outbreak was controlled at the end of 2007, but sporadic cases were identified until the end of 2009. A bundle of appropriate control measures may halt the spread of such outbreaks, provided that substantial human resources and financial support are available.
2006 年和 2007 年，法国北部爆发了大规模的艰难梭菌感染（CDI），其 PCR-核糖型为 027。总体而言，38 家医疗机构在 22 个月内报告了 529 例 CDI，包括 281 例实验室确诊的 CDI 027 和 248 例未确诊的 CDI 027 病例（每 10000 张择期病床发病率：1.63，范围：0.07 至 7.94）。这些病例主要发生在长期护理医院和养老院，靠近法国和比利时边境。在首次疫情高峰时，开展了一项主动监测和预防活动，包括医护人员的卫生防护措施，这有助于医疗机构改善护理组织。疫情在 2007 年底得到控制，但直到 2009 年底仍有散发病例。如果有大量的人力资源和财政支持，一整套适当的控制措施可能会阻止此类疫情的传播。
