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病毒爆发的决定因素有哪些,是否有可能预测其出现?

[What are the determinants of viral outbreaks and is it possible to predict their emergence?].

作者信息

Che Didier

机构信息

Direction des maladies infectieuses, Santé publique France, 12, rue du Val-d'Osne, 94415 Saint-Maurice cedex, France.

出版信息

Presse Med. 2019 Dec;48(12):1528-1535. doi: 10.1016/j.lpm.2019.10.012. Epub 2019 Nov 22.

Abstract

The emergence of a viral disease most often results from an imbalance in the interaction between the infectious agent, the host and the environment. After the introduction phase of a viral disease in a territory or a given population and once the first chains of transmission occur, the spread of the disease or its sustainability are possible if the control measures are not implemented or are not sufficiently effective. If it is difficult to anticipate the occurrence and introduction of an emerging viral disease, the following three key elements must be strengthened to limit its impact: (1) anticipation and preparation; (2) research and (3) monitoring and surveillance. Finally, to guarantee that the measures taken are relevant and acceptable to the population, a multidisciplinary approach must be systematically relied upon and re-evaluated on a prospective basis.

摘要

病毒性疾病的出现通常是由于感染源、宿主和环境之间相互作用失衡所致。在某一地区或特定人群中引入病毒性疾病阶段之后,一旦出现首批传播链,如果不实施控制措施或控制措施不够有效,疾病就可能传播或持续存在。虽然很难预测新发病毒性疾病的发生和引入,但必须强化以下三个关键要素以限制其影响:(1)预测与准备;(2)研究;(3)监测与监视。最后,为确保所采取的措施与民众相关且为民众所接受,必须系统地采用多学科方法,并前瞻性地进行重新评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2159/7127061/195f9f4cd6ef/gr1_lrg.jpg

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