Service de chirurgie digestive, hôpital Saint-Antoine, UPMC Paris-06, 75012 Paris, France.
J Visc Surg. 2010 Feb;147(1):e13-20. doi: 10.1016/j.jviscsurg.2010.02.004. Epub 2010 Mar 11.
Pancreatic fistula, the most dreaded complication of pancreatoduodenectomy occurs with an incidence ranging from 4-30% in literature reports; the incidence varies considerably according to the definition of fistula used. This literature review describes various methods proposed over the last decade to decrease the incidence and severity of pancreatic fistula including techniques of pancreatico-jejunal and pancreatico-gastric anastomoses, deliberate avoidance of pancreatico-enteric anastomosis, and the prophylactic role of somatostatin analogues.
胰瘘是胰十二指肠切除术最可怕的并发症，文献报道的发生率为 4%-30%；根据使用的瘘定义，发生率差异很大。本文综述了过去十年提出的各种降低胰瘘发生率和严重程度的方法，包括胰肠和胰胃吻合技术、故意避免胰肠吻合以及生长抑素类似物的预防作用。
