University Psychiatric Centre, University Hospital Gasthuisberg, Leuven, Belgium.
Digestion. 2010;82(4):201-10. doi: 10.1159/000269822. Epub 2010 Jun 24.
A new classification of functional gastrointestinal disorders (FGID) became available recently, based on consensus in expert committees ('Rome III process'). It is widely accepted that these frequent disorders, although their pathophysiology remains incompletely understood, result from a complex reciprocal interaction between biological, psychological and social factors that can be predisposing, precipitating and/or perpetuating. Comorbidity with psychiatric disorders, especially mood and anxiety disorders, is high. Modern epidemiologic, psychophysiological and functional neuroimaging studies have partially elucidated the mechanisms underlying the relation between cognitive-affective processes on the one hand and GI function and symptom reporting on the other. The aim of this article is to provide a noncomprehensive historical review of the literature on FGID up to the mid-20th century, with special emphasis on the role of psychosocial factors and psychiatric comorbidity. We can conclude from this review that a lot of the knowledge that became available recently through modern research methodology can also be found in the historical psychosomatic and neuroscience literature, though obviously less empirically grounded. This provides further support for an integrative, multidisciplinary biopsychosocial approach to FGID.
最近，基于专家委员会的共识（“罗马 III 进程”），出现了一种新的功能性胃肠疾病（FGID）分类。人们普遍认为，尽管这些常见疾病的病理生理学仍不完全清楚，但它们是由生物、心理和社会因素之间复杂的相互作用引起的，这些因素可能是促成、引发和/或持续存在的因素。与精神障碍的共病率很高，特别是情绪和焦虑障碍。现代流行病学、心理生理学和功能性神经影像学研究部分阐明了认知-情感过程与胃肠道功能和症状报告之间关系的机制。本文的目的是对截至 20 世纪中叶的 FGID 文献进行非全面的历史回顾，特别强调心理社会因素和精神共病的作用。从这篇综述中可以得出结论，通过现代研究方法获得的许多新知识也可以在历史心理生理学和神经科学文献中找到，尽管显然没有那么有经验依据。这为 FGID 的综合、多学科生物心理社会方法提供了进一步的支持。
