Centers for Disease Control and Prevention, Division of HIV/AIDS Prevention, 1600 Clifton Road, Mailstop E-46, Atlanta, GA 30333, USA.
J Clin Microbiol. 2010 Sep;48(9):3343-5. doi: 10.1128/JCM.01030-10. Epub 2010 Jun 30.
The Aptima HIV-1 RNA qualitative assay tested with a WHO-approved HIV type 1 RNA standard in 16- and 32-member pools detected 100% of the pools (1,070 and 2,130 HIV-1 RNA copies/ml/pool, respectively), thus exceeding the FDA-required lower limit of detection. The Aptima test can be used to screen for acute-phase HIV infection.
Aptima HIV-1 RNA 定性检测使用世界卫生组织批准的 HIV-1 RNA 标准品在 16 份和 32 份样本混合池进行检测,分别能够检出 100%的混合池(每份混合池的 HIV-1 RNA 拷贝数为 1,070 和 2,130/ml),超过了 FDA 要求的最低检测限。Aptima 检测可用于筛查急性期 HIV 感染。