评价 Gen-Probe Aptima HIV-1 RNA 定性检测作为替代 Western blot 分析用于确认 HIV 感染的方法。
Evaluation of the Gen-Probe Aptima HIV-1 RNA qualitative assay as an alternative to Western blot analysis for confirmation of HIV infection.
机构信息
Division of Infectious Diseases, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
出版信息
J Clin Microbiol. 2011 Apr;49(4):1642-5. doi: 10.1128/JCM.02183-10. Epub 2011 Feb 23.
Abstract
The Gen-Probe Aptima HIV-1 RNA qualitative assay was evaluated as an alternative to Western blot analysis for the confirmation of HIV infection using serum samples that were repeatedly reactive for HIV antibodies. The Aptima HIV assay readily discriminated between HIV-1-infected and -uninfected individuals and effectively reduced the number of indeterminate results relative to Western blot analysis.
摘要
基因探针 Aptima HIV-1 RNA 定性检测被评估为 Western blot 分析的替代方法，用于确认血清样本中 HIV 抗体反复呈阳性的 HIV 感染。Aptima HIV 检测能够很好地区分 HIV-1 感染和未感染个体，并与 Western blot 分析相比，有效减少了不确定结果的数量。
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