Wadsworth Center, New York State Department of Health, Albany, NY 12201-2002, USA.
J Clin Microbiol. 2011 Oct;49(10):3667-8. doi: 10.1128/JCM.00650-11. Epub 2011 Aug 10.
A 128-member specimen pooling scheme for acute HIV infection (AHI) detection was evaluated using 21 AHI specimens (range, 1,520 to 500,000 copies/ml) previously identified by RNA testing of 16-member plasma pools. HIV-1 RNA was detectable in 128-member pools for all 21 specimens; however, one pool created from a specimen with 1,827 copies/ml was nonreactive in one of three replicates.
采用 128 份样本混合方案对急性 HIV 感染（AHI）进行检测，该方案使用了 21 份先前通过 16 份血浆混合样本 RNA 检测确定的 AHI 样本（范围：1520 拷贝/ml 至 500000 拷贝/ml）。所有 21 个样本均能在 128 份混合样本中检测到 HIV-1 RNA；然而，有一份样本的浓度为 1827 拷贝/ml，其中一个 3 份重复的混合样本检测结果为阴性。
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