印度南部眼眶疾病谱：阿伐斯汀对 6328 例连续患者的研究。
Spectrum of orbital disease in South India: an aravind study of 6328 consecutive patients.
机构信息
Orbit and Oculoplasty Services, Aravind Eye Hospital, Madurai, Tamil Nadu, India.
出版信息
Ophthalmic Plast Reconstr Surg. 2010 Sep-Oct;26(5):315-22. doi: 10.1097/IOP.0b013e3181c32f2f.
AIM
To review the incidence of orbital diseases in South India and to compare with other case series published.
METHODS
Retrospective review of 6328 consecutive patients with orbital disease evaluated at Aravind Eye Hospital between January 1997 and December 2008. The main outcome measure was incidence of orbital disease in South Indian population, as determined by clinical and histopathologic criteria. A literature review was conducted to compare the results of this study with those of previously published reports.
RESULTS
Of the 6328 patients, 2161 (34.1%) had inflammatory orbital disease, 1965 (31.0%) had systemic conditions involving the orbit, 1277 (20.1%) had neoplasm, 600 (9.4%) had congenital lesions, 308 (4.8%) had trauma, and 17 (0.2%) had vascular disease. Of the 2161 patients presenting with inflammatory disease, 1473 (68.1%) had idiopathic orbital inflammation, 270 (12.5%) had infection, 126 (5.8%) had dacryoadenitis, and 292 (13.5%) had other etiologies. Among the 1965 patients presenting with systemic disease involving the orbit, 1938 (98.6%) were diagnosed with thyroid orbitopathy, 22 (1.1%) with amyloidosis, and 5 (0.2%) with sarcoidosis. Of the 1277 patients with neoplasm, the tumor was vascular in 369 (28.8%), neural in 336 (26.3%), lymphoid or leukemic in 131 (10.2%), secondary neoplasm in 82 (6.4%), epithelial in 68 (5.3%), adipose in 53 (4.1%), metastatic in 39 (3.0%), and fibrous, fibro-osseous, striated muscle, histiocytic, and other cellular origin in 40 (3.1%), 37 (2.8%), 23 (1.8%), 21 (1.6%), and 78 (6.1%), respectively. Of the 600 patients with congenital lesions, 427 (71.1%) had dermoid and 170 (28.3%) had dermolipoma, followed by meningoencephalocele.
CONCLUSIONS
The most common causes of orbital disease in South India are inflammatory (34.1%) and systemic conditions (31.0%). With the exception of higher incidence of inflammatory etiologies, these data are largely consistent with prior published reports.
目的
回顾印度南部眼眶疾病的发病率，并与其他已发表的病例系列进行比较。
方法
对 1997 年 1 月至 2008 年 12 月期间在阿拉文眼科医院就诊的 6328 例连续眼眶疾病患者进行回顾性分析。主要观察指标为临床和组织病理学标准确定的印度南部人群眼眶疾病的发病率。进行文献复习，将本研究结果与以往发表的报告进行比较。
结果
6328 例患者中，2161 例（34.1%）为炎性眼眶疾病，1965 例（31.0%）为累及眼眶的全身疾病，1277 例（20.1%）为肿瘤，600 例（9.4%）为先天性病变，308 例（4.8%）为外伤，17 例（0.2%）为血管性疾病。在 2161 例炎性疾病患者中，1473 例（68.1%）为特发性眼眶炎症，270 例（12.5%）为感染，126 例（5.8%）为泪腺炎，292 例（13.5%）为其他病因。在 1965 例累及眼眶的全身疾病患者中，1938 例（98.6%）诊断为甲状腺眼病，22 例（1.1%）为淀粉样变性，5 例（0.2%）为结节病。在 1277 例肿瘤患者中，血管源性肿瘤 369 例（28.8%），神经源性肿瘤 336 例（26.3%），淋巴或白血病 131 例（10.2%），继发性肿瘤 82 例（6.4%），上皮性肿瘤 68 例（5.3%），脂肪性肿瘤 53 例（4.1%），转移性肿瘤 39 例（3.0%），纤维性、纤维骨样、横纹肌、组织细胞源性肿瘤分别为 40 例（3.1%）、37 例（2.8%）、23 例（1.8%）、21 例（1.6%）和 78 例（6.1%）。在 600 例先天性病变患者中，427 例（71.1%）为皮样囊肿，170 例（28.3%）为皮脂瘤，其次为脑膜脑膨出。
结论
印度南部眼眶疾病最常见的原因是炎症（34.1%）和全身疾病（31.0%）。除炎症病因发病率较高外，这些数据与以往发表的报告基本一致。
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