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眼部淋巴瘤的认识与分类

Understanding and Classification of Ocular Lymphomas.

作者信息

White Valerie A

机构信息

WHO/IARC Classification of Tumours Group, International Agency for Research on Cancer, Lyon, France.

出版信息

Ocul Oncol Pathol. 2019 Oct;5(6):379-386. doi: 10.1159/000499845. Epub 2019 May 16.

DOI:10.1159/000499845
PMID:31768360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6872993/
Abstract

BACKGROUND

Lymphomas that involve the tissues of the ocular adnexae and the eye itself can be confusing for both the new and seasoned learner alike. In this review, I present a simple way of classifying these disorders that will help to facilitate understanding of these myriad entities.

SUMMARY

Classifications of lymphomas have changed significantly over the last 40 years, but in recent decades, the basic structure of the WHO classification has remained the same, facilitating understanding.

KEY MESSAGES

The ocular lymphomas can be divided into those that are external to the eye (ocular adnexae) and those that are internal (vitreoretinal and uveal). At each of these sites specific subtypes of lymphoma are common. Focusing on these common subtypes can aid the learner to create a scaffold that enables current understanding and upon which they can build for the future.

摘要

背景

累及眼附属器和眼本身组织的淋巴瘤,对于新手和经验丰富的学习者来说都可能令人困惑。在本综述中,我提出一种对这些疾病进行分类的简单方法,这将有助于促进对这些众多实体的理解。

总结

在过去40年里,淋巴瘤的分类发生了显著变化,但近几十年来,世界卫生组织(WHO)分类的基本结构保持不变,便于理解。

关键信息

眼部淋巴瘤可分为眼外(眼附属器)和眼内(玻璃体视网膜和葡萄膜)两类。在这些部位,特定的淋巴瘤亚型较为常见。关注这些常见亚型有助于学习者构建一个框架,以实现当前的理解,并为未来的学习打下基础。

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本文引用的文献

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Orbital Lymphoma-An International Multicenter Retrospective Study.眼眶淋巴瘤:一项国际多中心回顾性研究。
Am J Ophthalmol. 2019 Mar;199:44-57. doi: 10.1016/j.ajo.2018.11.002. Epub 2018 Nov 10.
2
Langerhans-Cell Histiocytosis.朗格汉斯细胞组织细胞增多症
N Engl J Med. 2018 Aug 30;379(9):856-868. doi: 10.1056/NEJMra1607548.
3
Orbital lymphoma.眼眶淋巴瘤。
Surv Ophthalmol. 2019 Jan-Feb;64(1):45-66. doi: 10.1016/j.survophthal.2018.08.002. Epub 2018 Aug 23.
4
Novel developments in the pathogenesis and diagnosis of extranodal marginal zone lymphoma.结外边缘区淋巴瘤发病机制与诊断的新进展
J Hematop. 2017 Sep 25;10(3-4):91-107. doi: 10.1007/s12308-017-0302-2. eCollection 2017 Dec.
5
Clinicopathological Features of Ocular Adnexal Mantle-Cell Lymphoma in an International Multicenter Cohort.眼附属器黏膜相关边缘区 B 细胞淋巴瘤的临床病理特征:一项国际多中心队列研究
JAMA Ophthalmol. 2017 Dec 1;135(12):1367-1374. doi: 10.1001/jamaophthalmol.2017.4810.
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Primary Vitreoretinal Lymphoma -- A Review.原发性玻璃体视网膜淋巴瘤——综述
Asia Pac J Ophthalmol (Phila). 2017 May-Jun;6(3):283-289. doi: 10.22608/APO.2017150.
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