Skalpe I O
Spine (Phila Pa 1976). 1978 Mar;3(1):61-4. doi: 10.1097/00007632-197803000-00012.
Late sequelae (adhesive arachnoiditis) have been reported following myelography with the oily contrast medium (Pantopaque) and with the ionic water-soluble contrast media methiodal sodium (Abrodil, Conturex, Kontrast U) meglumine iothalamate (Conray Meglumine) and meglumine iocarmate (Bis-Conray, Dimer-X). Adhesive arachnoiditis has not yet been reported after the use of the nonionic water-soluble contrast medium metrizamide (Amipaque). Thus, this is considered the contrast medium of choice for lumbar myelography. Using the recommended dose of 10 ml with an iodine concentration of 170 mg/ml for this examination, adhesive arachnoiditis is unlikely to occur. Increased osmolality of spinal fluid after injection of contrast medium is related to increased frequency of arachnoiditis.
使用油性造影剂（碘苯酯）以及离子型水溶性造影剂甲泛影钠（阿勃迪尔、康锐克斯、康锐斯特U）、碘他拉葡胺（康瑞）和碘卡明葡胺（双康瑞、二聚体X）进行脊髓造影后，已有迟发性后遗症（粘连性蛛网膜炎）的报道。使用非离子型水溶性造影剂甲泛葡胺（阿米培克）后尚未有粘连性蛛网膜炎的报道。因此，它被认为是腰椎脊髓造影的首选造影剂。对于该检查，使用推荐剂量的10毫升、碘浓度为170毫克/毫升的甲泛葡胺，发生粘连性蛛网膜炎的可能性不大。注射造影剂后脑脊液渗透压升高与蛛网膜炎发生率增加有关。
