细胞间相互作用基因的表达可区分HLXB9/TEL与MLL阳性儿童急性髓系白血病。 - Suppr

Expression of cell-cell interacting genes distinguishes HLXB9/TEL from MLL-positive childhood acute myeloid leukemia.

作者信息

Wildenhain S, Ruckert C, Röttgers S, Harbott J, Ludwig W-D, Schuster F R, Beldjord K, Binder V, Slany R, Hauer J, Borkhardt A

出版信息

Leukemia. 2010 Sep;24(9):1657-60. doi: 10.1038/leu.2010.146. Epub 2010 Jul 1.

DOI:10.1038/leu.2010.146

PMID:20596032

Abstract

摘要

相似文献

Expression of cell-cell interacting genes distinguishes HLXB9/TEL from MLL-positive childhood acute myeloid leukemia.细胞间相互作用基因的表达可区分HLXB9/TEL与MLL阳性儿童急性髓系白血病。

Leukemia. 2010 Sep;24(9):1657-60. doi: 10.1038/leu.2010.146. Epub 2010 Jul 1.

Identification of Mixed Lineage Leukemia Gene (MLL)/MLLT10 Fusion Transcripts by Reverse Transcription-PCR and Sequencing in a Case of AML With a FISH-Negative Cryptic MLL Rearrangement.通过逆转录聚合酶链反应和测序在一例荧光原位杂交阴性隐匿性混合系白血病基因（MLL）重排的急性髓系白血病病例中鉴定MLL/MLLT10融合转录本

Ann Lab Med. 2015 Jul;35(4):469-71. doi: 10.3343/alm.2015.35.4.469. Epub 2015 May 21.

A new rearrangement giving rise to a very rare MLL-MLLT10 fusion mRNA in an infant acute myeloid leukemia.一名婴儿急性髓系白血病中出现一种新的重排，产生了一种非常罕见的MLL-MLLT10融合mRNA。

Cancer Genet. 2015 Mar;208(3):101-2. doi: 10.1016/j.cancergen.2014.10.006. Epub 2014 Oct 25.

A partial nontandem duplication of the MLL gene in four patients with acute myeloid leukemia.

Cancer Genet Cytogenet. 2009 Dec;195(2):150-6. doi: 10.1016/j.cancergencyto.2009.05.008.

Expression of HOXB genes is significantly different in acute myeloid leukemia with a partial tandem duplication of MLL vs. a MLL translocation: a cross-laboratory study.HOXB基因在伴有MLL部分串联重复的急性髓系白血病与MLL易位的急性髓系白血病中的表达存在显著差异：一项跨实验室研究。

Cancer Genet. 2011 May;204(5):252-9. doi: 10.1016/j.cancergen.2011.02.003.

Hyperdiploidy and duplication of der(11)ins(10;11)(p12;q23q14) in acute myeloid leukemia with MLL/MLLT10 fusion gene.伴有MLL/MLLT10融合基因的急性髓系白血病中的超二倍体和der(11)ins(10;11)(p12;q23q14)重复

Leuk Lymphoma. 2013 Sep;54(9):2055-8. doi: 10.3109/10428194.2012.762094. Epub 2013 Jan 23.

Recurrent involvement of ring-type zinc finger genes in complex molecular rearrangements in childhood acute myelogeneous leukemia with translocation t(10;11)(p12;q23).环状锌指基因反复参与伴有t(10;11)(p12;q23)易位的儿童急性髓系白血病复杂分子重排。

Leukemia. 2013 Aug;27(8):1745-8. doi: 10.1038/leu.2013.1. Epub 2013 Jan 9.

Complex three-way translocation involving MLL, ELL, RREB1, and CMAHP genes in an infant with acute myeloid leukemia and t(6;19;11)(p22.2;p13.1;q23.3).一名患有急性髓系白血病且存在t(6;19;11)(p22.2;p13.1;q23.3)的婴儿中涉及MLL、ELL、RREB1和CMAHP基因的复杂三向易位。

Cytogenet Genome Res. 2013;141(1):7-15. doi: 10.1159/000351224. Epub 2013 May 30.

Abl-interactor 2 (ABI2): a novel MLL translocation partner in acute myeloid leukemia.Abl相互作用蛋白2（ABI2）：急性髓系白血病中一种新的MLL易位伙伴。

Leuk Res. 2012 May;36(5):e113-5. doi: 10.1016/j.leukres.2012.01.005. Epub 2012 Feb 1.

Analyzing acute leukemia patients with complex MLL rearrangements by a sequential LDI-PCR approach.通过连续长距离反向PCR方法分析具有复杂MLL重排的急性白血病患者。

Cancer Lett. 2013 Sep 28;338(2):249-54. doi: 10.1016/j.canlet.2013.03.029. Epub 2013 Apr 2.

引用本文的文献

Aberrant MNX1 expression associated with t(7;12)(q36;p13) pediatric acute myeloid leukemia induces the disease through altering histone methylation.异常 MNX1 表达与 t(7;12)(q36;p13) 儿童急性髓系白血病相关，通过改变组蛋白甲基化诱导疾病。

Haematologica. 2024 Mar 1;109(3):725-739. doi: 10.3324/haematol.2022.282255.

Mechanisms associated with t(7;12) acute myeloid leukaemia: from genetics to potential treatment targets.与 t(7;12) 急性髓系白血病相关的机制：从遗传学角度到潜在的治疗靶点。

Biosci Rep. 2023 Jan 31;43(1). doi: 10.1042/BSR20220489.

Engineered model of t(7;12)(q36;p13) AML recapitulates patient-specific features and gene expression profiles.t(7;12)(q36;p13)急性髓系白血病的工程模型概括了患者特异性特征和基因表达谱。

Oncogenesis. 2022 Sep 3;11(1):50. doi: 10.1038/s41389-022-00426-2.

LncRNA MNX1-AS1 promotes progression of intrahepatic cholangiocarcinoma through the MNX1/Hippo axis.长链非编码 RNA MNX1-AS1 通过 MNX1/Hippo 轴促进肝内胆管癌的进展。

Cell Death Dis. 2020 Oct 22;11(10):894. doi: 10.1038/s41419-020-03029-0.

Novel insights into the role of aberrantly expressed MNX1 (HLXB9) in infant acute myeloid leukemia.对异常表达的MNX1（HLXB9）在婴儿急性髓系白血病中作用的新见解。

Haematologica. 2019 Jan;104(1):1-3. doi: 10.3324/haematol.2018.205971.

The homeobox transcription factor HB9 induces senescence and blocks differentiation in hematopoietic stem and progenitor cells.同源盒转录因子 HB9 诱导造血干细胞和祖细胞衰老并阻止其分化。

Haematologica. 2019 Jan;104(1):35-46. doi: 10.3324/haematol.2018.189407. Epub 2018 Aug 9.

Paediatric acute myeloid leukaemia with the t(7;12)(q36;p13) rearrangement: a review of the biological and clinical management aspects.伴有t(7;12)(q36;p13)重排的儿童急性髓系白血病：生物学及临床管理方面综述

Biomark Res. 2015 Oct 5;3:21. doi: 10.1186/s40364-015-0041-4. eCollection 2015.

A Novel Three-Colour Fluorescence in Situ Hybridization Approach for the Detection of t(7;12)(q36;p13) in Acute Myeloid Leukaemia Reveals New Cryptic Three Way Translocation t(7;12;16).一种新型的三色荧光原位杂交方法用于检测急性髓系白血病中的 t(7;12)(q36;p13)，揭示了新的隐匿性三向易位 t(7;12;16)。

Cancers (Basel). 2013 Mar 11;5(1):281-95. doi: 10.3390/cancers5010281.

The embryonic transcription factor Hlxb9 is a menin interacting partner that controls pancreatic β-cell proliferation and the expression of insulin regulators.胚胎转录因子 Hlxb9 是与 menin 相互作用的伙伴，它控制着胰腺 β 细胞的增殖和胰岛素调节因子的表达。

Endocr Relat Cancer. 2013 Feb 18;20(1):111-22. doi: 10.1530/ERC-12-0077. Print 2013 Feb.

Homeobox protein HB9 binds to the prostaglandin E receptor 2 promoter and inhibits intracellular cAMP mobilization in leukemic cells.同源盒蛋白 HB9 与前列腺素 E 受体 2 启动子结合，抑制白血病细胞内 cAMP 的动员。

J Biol Chem. 2012 Nov 23;287(48):40703-12. doi: 10.1074/jbc.M111.308965. Epub 2012 Oct 8.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

Expression of cell-cell interacting genes distinguishes HLXB9/TEL from MLL-positive childhood acute myeloid leukemia.

作者信息

出版信息

相似文献

引用本文的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

相似文献

引用本文的文献