Milisavljevic D, Zivic M, Radovanović Z, Stankovic P
Hippokratia. 2010 Apr;14(2):133-5.
Madelung's disease (benign symmetrical lipomatosis) is a rare disease of unknown etiology manifesting as symmetric abnormal deposits of adipose tissue in the head, neck and upper trunk. We report a case of a 58-year-old man with a long lasting Madelungs disease in whom progressive fatty tissue accumulation caused a severe inspiratory dyspnea as atypical presenting symptom. The etiopathogenetic, clinico-diagnostic and therapeutic aspects of this rare disease are discussed. Due to its progressive but not so easily predictable enlarging behavior Madelung's disease has not only aesthetic but also functional and sometimes life threatening consequences which need to be treated.
马德隆氏病（良性对称性脂肪瘤病）是一种病因不明的罕见疾病，表现为头颈部和上躯干脂肪组织的对称性异常沉积。我们报告一例58岁男性患有长期马德隆氏病，其进行性脂肪组织堆积导致严重吸气性呼吸困难作为非典型表现症状。本文讨论了这种罕见疾病的病因、临床诊断和治疗方面。由于马德隆氏病具有进行性但不太容易预测的增大行为，它不仅有美学影响，还会产生功能影响，有时甚至危及生命，需要进行治疗。
