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一名绝经前女性患有多器官转移的子宫内膜样腺癌。

Endometrioid endometrial adenocarcinoma in a premenopausal woman with multiple organ metastases.

作者信息

Srikantia Nirmala, B Rekha, A G Rajeev, Kalyan Suman N

机构信息

Department of Radiotherapy, M S Ramaiah Medical College and Hospital, MSRIT Post, Bangalore - 560085.

出版信息

Indian J Med Paediatr Oncol. 2009 Apr;30(2):80-3. doi: 10.4103/0971-5851.60053.

DOI:10.4103/0971-5851.60053
PMID:20596308
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2885881/
Abstract

Endometrial adenocarcinoma is the third common malignancy of the female genital tract occurring most often in the postmenopausal age group. High tumor grade, advanced surgical stage, and lymphovascular space invasion are implicated as poor prognostic factors for dissemination of disease. We present an unusual case of endometrial adenocarcinoma in a premenopausal woman with simultaneous metastases in brain, liver, skin and skeletal system, within one month of completion of treatment. The role of adjuvant/concurrent chemotherapy in addition to radiotherapy in high risk cases is discussed along with the review of literature.

摘要

子宫内膜腺癌是女性生殖道第三常见的恶性肿瘤,最常发生于绝经后年龄组。高肿瘤分级、手术分期晚以及淋巴管间隙浸润被认为是疾病播散的不良预后因素。我们报告了一例绝经前女性子宫内膜腺癌的罕见病例,在完成治疗后的一个月内,脑、肝、皮肤和骨骼系统同时出现转移。本文结合文献复习,讨论了高危病例中辅助/同步化疗联合放疗的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8aa/2885881/2bb02ff9efd2/IJMPO-30-80-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8aa/2885881/49f6404fe859/IJMPO-30-80-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8aa/2885881/a4c3f3bea27f/IJMPO-30-80-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8aa/2885881/46b44cdc56c7/IJMPO-30-80-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8aa/2885881/b813d08a543f/IJMPO-30-80-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8aa/2885881/2bb02ff9efd2/IJMPO-30-80-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8aa/2885881/49f6404fe859/IJMPO-30-80-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8aa/2885881/a4c3f3bea27f/IJMPO-30-80-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8aa/2885881/46b44cdc56c7/IJMPO-30-80-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8aa/2885881/b813d08a543f/IJMPO-30-80-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8aa/2885881/2bb02ff9efd2/IJMPO-30-80-g005.jpg

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本文引用的文献

1
Lymph-vascular space involvement and outer one-third myometrial invasion are strong predictors of distant haematogeneous failures in patients with stage I-II endometrioid-type endometrial cancer.在I-II期子宫内膜样型子宫内膜癌患者中,淋巴管间隙受累和肌层外三分之一浸润是远处血行转移失败的有力预测指标。
Anticancer Res. 2009 May;29(5):1715-20.
2
[Gynecologic cancer].[妇科癌症]
Gan To Kagaku Ryoho. 2008 Sep;35(9):1488-94.
3
Adjuvant chemotherapy as treatment of high-risk stage I and II endometrial cancer.辅助化疗作为高危Ⅰ期和Ⅱ期子宫内膜癌的治疗方法。
BCL-2在子宫内膜癌中的免疫组化表达及其与激素受体状态和表皮生长因子的比较
Cureus. 2023 Jan 4;15(1):e33346. doi: 10.7759/cureus.33346. eCollection 2023 Jan.
4
Machine Learning for Endometrial Cancer Prediction and Prognostication.用于子宫内膜癌预测和预后评估的机器学习
Front Oncol. 2022 Jul 27;12:852746. doi: 10.3389/fonc.2022.852746. eCollection 2022.
5
Testosterone-Secreting Endometrioid Ovarian Carcinoma Presenting With Hyperandrogenism.以高雄激素血症为表现的分泌睾酮的子宫内膜样卵巢癌。
AACE Clin Case Rep. 2022 Jan 25;8(3):135-138. doi: 10.1016/j.aace.2022.01.003. eCollection 2022 May-Jun.
6
High-intermediate risk endometrial cancer: moving toward a molecularly based risk assessment profile.高-中风险子宫内膜癌:朝着基于分子的风险评估特征迈进。
Int J Clin Oncol. 2022 Feb;27(2):323-331. doi: 10.1007/s10147-021-02089-2. Epub 2022 Jan 17.
7
Combined Open and Endoscopic Endonasal Skull Base Resection of a Rare Endometrial Carcinoma Metastasis.开放手术联合鼻内镜下经鼻颅底切除术治疗罕见的子宫内膜癌转移瘤
J Neurol Surg Rep. 2018 Jan;79(1):e9-e13. doi: 10.1055/s-0038-1635098. Epub 2018 Feb 22.
Gynecol Oncol. 2004 Aug;94(2):333-9. doi: 10.1016/j.ygyno.2004.05.040.
4
Current treatment options for endometrial cancer.子宫内膜癌的当前治疗选择。
Expert Rev Anticancer Ther. 2004 Aug;4(4):679-89. doi: 10.1586/14737140.4.4.679.
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Brain metastases from endometrial carcinoma: a retrospective study.子宫内膜癌脑转移:一项回顾性研究。
Gynecol Oncol. 2004 May;93(2):524-8. doi: 10.1016/j.ygyno.2004.02.006.
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Preliminary analysis of RTOG 9708: Adjuvant postoperative radiotherapy combined with cisplatin/paclitaxel chemotherapy after surgery for patients with high-risk endometrial cancer.放射治疗肿瘤学组(RTOG)9708初步分析:高危子宫内膜癌患者术后辅助性放疗联合顺铂/紫杉醇化疗。
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