Sabella S, Brunetti V, Vecchio G, Torre A Della, Rinaldi R, Cingolani R, Pompa P P
Nanoscale Res Lett. 2009 Jul 14;4(10):1222-1229. doi: 10.1007/s11671-009-9386-7.
We describe the design and optimization of a reliable strategy that combines self-assembly and lithographic techniques, leading to very precise micro-/nanopositioning of biomolecules for the realization of micro- and nanoarrays of functional DNA and antibodies. Moreover, based on the covalent immobilization of stable and versatile SAMs of programmable chemical reactivity, this approach constitutes a general platform for the parallel site-specific deposition of a wide range of molecules such as organic fluorophores and water-soluble colloidal nanocrystals. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s11671-009-9386-7) contains supplementary material, which is available to authorized users.
我们描述了一种可靠策略的设计与优化,该策略结合了自组装和光刻技术,能够实现生物分子的非常精确的微/纳米定位,以实现功能性DNA和抗体的微阵列和纳米阵列。此外,基于具有可编程化学反应性的稳定且通用的自组装单分子层的共价固定,这种方法构成了一个通用平台,用于多种分子(如有机荧光团和水溶性胶体纳米晶体)的平行位点特异性沉积。电子补充材料:本文的在线版本(doi:10.1007/s11671-009-9386-7)包含补充材料,授权用户可获取。