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内镜检查对儿童慢性腹痛管理的影响。

Impact of endoscopy on management of chronic abdominal pain in children.

机构信息

The Section of Pediatric Gastroenterology, Hepatology and Nutrition at Baylor College of Medicine, Houston, TX 77030, USA.

出版信息

Dig Dis Sci. 2011 Feb;56(2):488-93. doi: 10.1007/s10620-010-1315-1. Epub 2010 Jul 2.

Abstract

BACKGROUND

Endoscopy is performed frequently in children with chronic abdominal pain (CAP), but its impact on clinical management is unclear.

AIMS

We aimed to examine the frequency of changes in immediate medical management resulting from endoscopy with biopsy evaluating CAP in children.

METHODS

We conducted a prospective cross-sectional study to assess the frequency and determinants of management change in children who underwent endoscopy for evaluation of chronic abdominal pain. Patients were screened prior to undergoing endoscopy according to inclusion criteria. Each endoscopist was contacted prior to performing endoscopy and recorded a management plan if endoscopy could not be performed. These responses were compared with management recommendations by the same physician after the endoscopy and review of histopathology.

RESULTS

We analyzed 92 endoscopic procedures [63 esophagogastroduodenoscopies (EGDs) and 29 EGD/colonoscopy] performed in 92 children (mean age 11.6 years) with CAP. Overall, gastroenterologists changed management plans post endoscopy in 61 (66.3%) patients. In 46 (75%) of these cases, management was changed as a direct result of endoscopic or histologic findings. Overall, management changes included: reassurance in 17 cases, dietary changes in 6 cases, proton pump inhibitor (PPI) trial in 11 cases, antispasmodic/anticholinergic medication trials in 4 cases, and food allergy testing in 4 cases. No significant association was found between management changes and type of histologic findings or presence of alarm symptoms.

CONCLUSIONS

The overall rate of management change after endoscopic evaluation in children with CAP was approximately 66% (61/92). Management outcome was not associated with type of histologic findings.

摘要

背景

在患有慢性腹痛(CAP)的儿童中经常进行内镜检查,但内镜检查对临床管理的影响尚不清楚。

目的

我们旨在研究通过内镜活检评估儿童 CAP 时,直接医疗管理变化的频率及其决定因素。

方法

我们进行了一项前瞻性横断面研究,以评估因慢性腹痛而行内镜检查的儿童中管理变化的频率和决定因素。根据纳入标准,在进行内镜检查之前对患者进行筛选。在进行内镜检查之前,联系了每位内镜医生,并记录了如果无法进行内镜检查的管理计划。这些反应与内镜检查后和组织病理学检查后同一医生的管理建议进行了比较。

结果

我们分析了 92 例内镜检查程序[63 例食管胃十二指肠镜检查(EGD)和 29 例 EGD/结肠镜检查],这些程序是在 92 例 CAP 患儿中进行的(平均年龄 11.6 岁)。总体而言,胃肠病医生在 61 例(66.3%)患儿中改变了内镜检查后的管理计划。在这些病例中,有 46 例(75%)是直接根据内镜或组织学发现改变管理的。总体而言,管理变化包括:17 例患者得到安抚,6 例患者改变饮食,11 例患者进行质子泵抑制剂(PPI)试验,4 例患者进行抗痉挛/抗胆碱能药物试验,4 例患者进行食物过敏测试。管理变化与组织学发现类型或报警症状的存在之间未发现显著相关性。

结论

在患有 CAP 的儿童中,内镜评估后管理变化的总体率约为 66%(61/92)。管理结果与组织学发现类型无关。

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