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[研究瑞马索在内毒素血症条件下治疗呼吸窘迫综合征的疗效]

[Studying efficacy of remaxol in the treatment of respiratory distress syndrome under endotoxicosis conditions].

作者信息

Vlasov A P, Nachkina E I, Grigor'eva T I, Tarasova T V, Potianova I V

出版信息

Eksp Klin Farmakol. 2010 May;73(5):23-6.

PMID:20597366
Abstract

Chronic model experiments on dogs showed that the development of respiratory distress syndrome under acute pancreatitis conditions is correlated with violation of metabolic processes in the lung tissue, which is caused by activation of the coagulation/lysis system and changes in the lipid metabolism. It is established that remaxol limits the development of inflammatory processes in lungs, produces correction of the lipid metabolism, and introduces positive changes in the coagulation system lung tissues under acute pancreatitis conditions.

摘要

犬的慢性模型实验表明,急性胰腺炎情况下呼吸窘迫综合征的发生与肺组织代谢过程的紊乱相关,这是由凝血/纤溶系统的激活和脂质代谢变化所引起的。已证实,瑞马唑仑在急性胰腺炎情况下可限制肺部炎症过程的发展,纠正脂质代谢,并使肺组织凝血系统发生积极变化。

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