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通过包埋聚丙烯嵌段聚(聚乙烯基吡咯烷酮)对聚丙烯进行表面生物相容性修饰。

Surface biocompatible modification of polypropylene by entrapment of polypropylene-block-poly(vinylpyrrolidone).

机构信息

School of Science, Shantou University, Shantou 515063, China.

出版信息

Colloids Surf B Biointerfaces. 2010 Oct 15;80(2):200-5. doi: 10.1016/j.colsurfb.2010.06.003. Epub 2010 Jun 15.

Abstract

A macromolecular surface modifier, namely polypropylene-block-poly(vinylpyrrolidone) copolymer, could diffuse preferably onto the surface and effectively increased the biocompatibility of PP. The blood and cell compatibilities of PP and PP-b-PVP/PP blend films were evaluated by determination of the extent of platelet adsorption, plasma recalcification time, hemolysis rate and cell proliferation using smooth muscle cells from rabbit aorta. The results revealed that the blood and cell compatibilities of PP were improved significantly by entrapment of a few PP-b-PVP copolymers in PP.

摘要

一种高分子表面改性剂,即聚丙烯嵌段聚(乙烯基吡咯烷酮)共聚物,可以更好地扩散到表面,并有效地提高了 PP 的生物相容性。通过测定血小板吸附程度、血浆复钙时间、溶血率和用兔主动脉平滑肌细胞进行细胞增殖,评估了 PP 和 PP-b-PVP/PP 共混膜的血液和细胞相容性。结果表明,将少量 PP-b-PVP 共聚物包埋在 PP 中,可显著改善 PP 的血液和细胞相容性。

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