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尼日利亚高原州人类钩端螺旋体病的血清学和培养检查

Serological and cultural examination for human leptospirosis in Plateau State, Nigeria.

作者信息

Ezeh A O, Adesiyun A A, Addo P B, Ellis W A, Makinde A A, Bello C S

机构信息

National Veterinary Research Institute, Vom, Nigeria.

出版信息

Cent Afr J Med. 1991 Jan;37(1):11-5.

PMID:2060002
Abstract

In a serological examination of 710 serum samples collected from human volunteers in Plateau State, Nigeria, 128 (18.0pc) had leptospiral antibody titres of 1:100 and above. The prevalence of antibodies to individual serovars were: hardjo 28 (21.9pc), pomona 18 (14.1pc), canicola 17 (13.3pc), grippotyphosa 15 (11.7pc), pyrogenes 13 (10.2pc), icterohaemorrhagiae 12 (0.4pc) and autumnalis 8 (6.3pc). There was no statistical difference in the prevalence rate of leptospirosis in the different local government areas (p greater than 0.05; X2). Among the occupational groups examined, the abattoir workers were particularly at risk with a prevalence rate of 29.5pc. A leptospiral variant of strain Hardjoprajitno was also isolated from the midstream urine of an abattoir worker who was apparently healthy. The isolation of Leptospira interrogans serovar hardjo in man is the first such report in Nigeria.

摘要

在对从尼日利亚高原州人类志愿者采集的710份血清样本进行的血清学检查中,128份(18.0%)的钩端螺旋体抗体效价达到1:100及以上。针对各个血清型的抗体流行率分别为:哈焦型28份(21.9%)、波摩那型18份(14.1%)、犬型17份(13.3%)、七日热型15份(11.7%)、致热型13份(10.2%)、出血黄疸型12份(0.4%)和秋季热型8份(6.3%)。不同地方政府区域的钩端螺旋体病流行率无统计学差异(p大于0.05;卡方检验)。在所检查的职业群体中,屠宰场工人尤其面临风险,流行率为29.5%。还从一名表面健康的屠宰场工人的中段尿中分离出哈焦普拉吉诺菌株的钩端螺旋体变种。在人类中分离出问号钩端螺旋体血清型哈焦型,这在尼日利亚尚属首次报告。

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