养老院中患有晚期痴呆症的居民的死亡预测因素。
Predictors of mortality in nursing home residents with advanced dementia.
机构信息
Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.
出版信息
Am J Alzheimers Dis Other Demen. 2010 Aug;25(5):439-45. doi: 10.1177/1533317510370955. Epub 2010 Jul 2.
Abstract
This analysis uses data from the Care of Nursing Home Residents with Advanced Dementia (CareAD) study to investigate which factors increase the risk of death in patients who are in the advanced stages of dementia. The hypothesis of this analysis was that specific illnesses with known high mortality would be associated with increased risk of death in the population of nursing home residents with advanced dementia, after controlling for demographic variables and disease-stage variables. Baseline data on 123 end-stage dementia nursing home residents were analyzed with a Cox proportional hazards regression. Of the comorbidities studied, pneumonia was the only illness significantly associated with shortened survival. This information can help health care professionals assist surrogate decision makers in making medical decisions regarding the treatment of comorbid medical illness in persons with advanced dementia.
摘要
本分析使用了来自《养老院中晚期痴呆患者护理（CareAD）研究》的数据，旨在探讨哪些因素会增加处于晚期痴呆阶段的患者的死亡风险。本分析的假设是，在控制人口统计学变量和疾病阶段变量后，具有已知高死亡率的特定疾病与养老院中晚期痴呆患者的死亡风险增加相关。对 123 名终末期痴呆养老院居民的基线数据进行了 Cox 比例风险回归分析。在所研究的合并症中，肺炎是唯一与生存时间缩短显著相关的疾病。这些信息可以帮助医疗保健专业人员协助替代决策者在治疗晚期痴呆患者的合并症方面做出医疗决策。
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